{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T11:51:12Z","timestamp":1777895472073,"version":"3.51.4"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T00:00:00Z","timestamp":1608076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>While sarcopenia is an important predictor of LT outcomes in adults, few studies have examined the association of sarcopenia with LT outcomes in pediatric patients. We investigated the clinical influence of sarcopenia on the post\u2010transplant outcomes in infants with BA. To define sarcopenia in infants, the cross\u2010sectional area of the tPMA in 93 healthy control infants was measured by computed tomography. Sarcopenia was defined as a tPMA lower than two standard deviations below the mean of healthy control infants. Eighty\u2010nine infants with BA with a median age at LT of 7.6\u00a0months old were enrolled. The clinical characteristics and outcomes of LT were verified in the sarcopenia group (n\u00a0=\u00a021) and non\u2010sarcopenia group (n\u00a0=\u00a068). The sarcopenia group had a significantly longer operation time and greater blood loss during LT than the non\u2010sarcopenia group (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.03 and 0.02). The incidence of portal vein stenosis and post\u2010operative bloodstream infection was also significantly higher in the sarcopenia group than in the non\u2010sarcopenia group (23.8% vs 4.4%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.02 and 28.6% vs 10.3%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.04, respectively). The total length of hospital stay did not differ significantly. The 1\u2010year patient and graft survival rates tended to be lower in the sarcopenia group than in the non\u2010sarcopenia group (90.5% vs 98.5%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.07 and 85.7% vs 97.1%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.05, respectively). Sarcopenia in infants with BA may be associated with the patient survival and serve as an effective marker for post\u2010operative outcomes of LT.<\/jats:p>","DOI":"10.1111\/petr.13950","type":"journal-article","created":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T20:40:42Z","timestamp":1608237642000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Impact of sarcopenia in infants with liver transplantation for biliary atresia"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8316-3523","authenticated-orcid":false,"given":"Masahiro","family":"Takeda","sequence":"first","affiliation":[{"name":"Organ Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3031-7319","authenticated-orcid":false,"given":"Seisuke","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Organ Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2441-5158","authenticated-orcid":false,"given":"Hajime","family":"Uchida","sequence":"additional","affiliation":[{"name":"Organ Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6985-945X","authenticated-orcid":false,"given":"Seiichi","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Organ Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Yanagi","sequence":"additional","affiliation":[{"name":"Organ Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4684-0446","authenticated-orcid":false,"given":"Akinari","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Organ Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Nosaka","sequence":"additional","affiliation":[{"name":"Department of Radiology National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1651-0430","authenticated-orcid":false,"given":"Mureo","family":"Kasahara","sequence":"additional","affiliation":[{"name":"Organ 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