{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T14:34:18Z","timestamp":1778510058854,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Strongyloides spp hyperinfections are a worldwide phenomenon that proves fatal for solid organ transplant recipients. Screening protocols to guide prophylaxis management vary institution to institution from universal to epidemiology driven. Our institution initiated a universal screening protocol regardless of travel history and exposure to ensure no cases were missed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this study, we describe the outcomes of three Strongyloides sero\u2010positive children whom underwent intestinal or liver transplantation and the experience of universal screening at a tertiary care county hospital in South Florida.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 66 intestine and liver pediatric transplant recipients who were screened for Strongyloides antibodies, only three were identified to be sero\u2010positive via the screening mechanism. Two of three had significant epidemiology risk factors. None of the patients reviewed were found to have developed hyperinfection. However, reflecting on the experience represented by our series of pediatric patients, the risk of any complication related to Strongyloides status appears low. Even among this South Florida population whom come from or travel to endemic regions are in contact with sero\u2010positive individuals, very few illustrate sero\u2010positivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>While institutions continue to analyze the cost\u2010benefit of universal testing vs. universal prophylaxis vs. targeted screening, the decision must encompass the patient population, rolling cumulative incidence, and morbidity and mortality related to this disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14039","type":"journal-article","created":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T14:04:25Z","timestamp":1621346665000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Describing universal Strongyloides serologic screening among pediatric intestinal and liver transplant recipients"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6584-7048","authenticated-orcid":false,"given":"Brandon","family":"Chatani","sequence":"first","affiliation":[{"name":"Pediatric Infectious Diseases University of Miami Miller School of Medicine Miami Transplant Institute\/Jackson Health System Miami FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gennaro","family":"Selvaggi","sequence":"additional","affiliation":[{"name":"Transplant Surgery Miami Transplant Institute Miami FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Garcia","sequence":"additional","affiliation":[{"name":"Pediatric Gastroenterology University of Miami Miller School of Medicine Miami Transplant Institute\/Jackson Health System Miami FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1316-1159","authenticated-orcid":false,"given":"Ivan A.","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Pediatric Infectious Diseases University of Miami Miller School of Medicine Miami Transplant Institute\/Jackson Health System Miami FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,18]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13137"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2018.04.012"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12666"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12954"},{"key":"e_1_2_11_6_1","first-page":"844","article-title":"Strongyloides infection among patients at a long\u2010term care facility \u2010 Florida, 2010\u20132012","volume":"62","author":"Leapley A","year":"2013","journal-title":"MMWR Morb Mortal Wkly 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