{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T17:20:23Z","timestamp":1755796823520,"version":"3.41.2"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T00:00:00Z","timestamp":1629072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The impact of the COVID pandemic on liver transplant (LT) programs varied among countries. Few data are available about that impact in pediatric liver transplant (PLT) programs. This study aimed at comparing the data of our program in Brazil (2019 vs. 2020).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and seventy\u2010four PLT were performed in the period (93% living donors). Patients were divided into two groups according to the LT date: pre\u2010COVID\u201019 period (march\/2019\u2013February\/2020) and COVID\u201019 period (March\/2020\u2013February 2021). In the pre\u2010COVID\u201019 period, 97 LTs were performed, and 77 LTs were performed in the COVID\u201019 period. Patients in the COVID\u201019 period were younger (10.9\u00a0months vs. 16\u00a0months, p 0.009), had higher PELD scores (15 vs. 14, p 0.04), more ascites (66.2 vs. 51.5%, p 0.03), and more frequently hospitalized before LT (27.3 vs. 17.5%). However, there was no difference in post\u2010LT complications, retransplantation nor survival rates. Six (6.2%) patients from pre\u2010COVID\u201019 period were COVID positive at a median of 15.5\u00a0months (14\u201317.5), and 6 (7.8%) patients from COVID\u201019 period were COVID positive at a median of 3\u00a0months (20\u00a0days\u20136\u00a0months) from LT. There was neither mortality nor complications in those patients. Four (33%) were hospitalized, and one had prolonged intubation. Four (33%) were asymptomatic, 4 (33%) had upper airways symptoms, and the remaining had gastrointestinal symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Overall, PLT was not affected during COVID\u201019 period. Even though patients from COVID\u201019 period were sicker, there was no significant impact in LT outcomes. All the recipients who tested positive for COVID had a favorable outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14112","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T07:06:44Z","timestamp":1629097604000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Pediatric liver transplantation activity in a high\u2010volume program during the COVID\u201019 pandemic in Brazil"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4712-9533","authenticated-orcid":false,"given":"Eduardo A.","family":"Fonseca","sequence":"first","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital S\u00edrio\u2010Liban\u00eas S\u00e3o Paulo Brazil"},{"name":"Hepatology and Liver Transplantation A. C. Camargo Cancer Center S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1339-2990","authenticated-orcid":false,"given":"Flavia","family":"Feier","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Santa Casa de Porto Alegre Porto Alegre Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1167-6829","authenticated-orcid":false,"given":"Renata","family":"Pugliese","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital S\u00edrio\u2010Liban\u00eas S\u00e3o Paulo Brazil"},{"name":"Hepatology and Liver Transplantation A. C. 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Camargo Cancer Center S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1997-4967","authenticated-orcid":false,"given":"Irene","family":"Miura","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital S\u00edrio\u2010Liban\u00eas S\u00e3o Paulo Brazil"},{"name":"Hepatology and Liver Transplantation A. C. Camargo Cancer Center S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"Baggio","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital S\u00edrio\u2010Liban\u00eas S\u00e3o Paulo Brazil"},{"name":"Hepatology and Liver Transplantation A. C. 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Camargo Cancer Center S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8716-3467","authenticated-orcid":false,"given":"Rodrigo","family":"Vincenzi","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital S\u00edrio\u2010Liban\u00eas S\u00e3o Paulo Brazil"},{"name":"Hepatology and Liver Transplantation A. C. Camargo Cancer Center S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7908-8268","authenticated-orcid":false,"given":"Karina","family":"Roda","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital S\u00edrio\u2010Liban\u00eas S\u00e3o Paulo Brazil"},{"name":"Hepatology and Liver Transplantation A. C. Camargo Cancer Center S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caio V.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital S\u00edrio\u2010Liban\u00eas S\u00e3o Paulo Brazil"},{"name":"Hepatology and Liver Transplantation A. C. Camargo Cancer Center S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9931-811X","authenticated-orcid":false,"given":"Paulo","family":"Chapchap","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital S\u00edrio\u2010Liban\u00eas S\u00e3o Paulo Brazil"},{"name":"Hepatology and Liver Transplantation A. C. 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