{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:33:27Z","timestamp":1753878807927,"version":"3.41.2"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,9,5]],"date-time":"2021-09-05T00:00:00Z","timestamp":1630800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>LT is the standard of care for many pediatric liver disorders. Although long\u2010term outcomes have improved, some rare complications such as transmission of occult donor tumors have been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case report<\/jats:title><jats:p>An adolescent diagnosed with tyrosinemia was submitted to LT from a previous healthy donor due to HCC. Almost 8\u00a0months after LT, the patient presented a nodular hepatic lesion. Clinically, he had mild weight loss, lower limb edema, and gynecomastia. Thorax CT found lesions in the left lung parenchyma, which showed no increased uptake in PET SCAN. Liver biopsy revealed a carcinoma with desmoplastic stroma. ISS was withdrawn, and palliative chemotherapy was started for presumptive HCC relapse. AFP remained normal, but HCG had reached unexpected values of 1984\u00a0IU\/L. As we requested detailed information about the other organ recipients from the same donor, we found that one of them passed away due to disseminated tumor. Five months after the beginning of chemotherapy, the patient underwent resection of liver segments V and VI. Histological examination confirmed liver metastatic choriocarcinoma. At the time of writing, with 11\u00a0years of follow\u2010up, the patient had sustained remission with no signs of relapse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>This case reports a diagnostic challenge in an adolescent with a particular unique background and a very rare pattern of tumor transmission. The authors aim to highlight the risk of cancer\u2010bearing organs reveled post\u2010LT and to testimony the experience of the successful outcome after a choriocarcinoma transmitted by liver graft.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14135","type":"journal-article","created":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T02:41:48Z","timestamp":1630896108000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Long\u2010term survival after choriocarcinoma transmitted by liver graft: A successful report in pediatric transplantation"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1033-4736","authenticated-orcid":false,"given":"In\u00eas","family":"Pessanha","sequence":"first","affiliation":[{"name":"Servi\u00e7o de Cirurgia Pedi\u00e1trica e Queimados Hospital Pedi\u00e1trico de Coimbra Centro Hospitalar e Universit\u00e1rio de Coimbra Coimbra Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00e1tima","family":"Heitor","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Oncologia Pedi\u00e1trica Hospital Pedi\u00e1trico de Coimbra Centro Hospitalar e Universit\u00e1rio de Coimbra Coimbra Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuel","family":"Furtado","sequence":"additional","affiliation":[{"name":"Unidade de Hepatologia e Transplanta\u00e7\u00e3o Hep\u00e1tica de Adultos Centro Hospitalar e Universit\u00e1rio de Coimbra Coimbra Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio Pedro","family":"Campos","sequence":"additional","affiliation":[{"name":"Unidade de Cuidados Respirat\u00f3rios e Nutricionais Hospital Dona Estef\u00e2nia Centro Hospitalar Lisboa Central Lisboa 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