{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T18:14:36Z","timestamp":1780596876787,"version":"3.54.1"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,12,19]],"date-time":"2021-12-19T00:00:00Z","timestamp":1639872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Infants with biliary atresia (BA) generally have chronic malnutrition. However, the best anthropometric measure to assess malnutrition and its correlation with disease severity is unknown. We aimed to assess correlations of various anthropometric measurements, including air displacement plethysmography (ADP), with laboratory parameters and with the pediatric end\u2010stage liver disease (PELD) score in infants with BA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Infants with BA were followed at a pediatric liver transplantation center during 2014\u20132018. Follow\u2010up comprised laboratory tests and nutritional assessment by a dietitian including dietary intake, weight, height, mid\u2010upper arm circumference (MUAC), and skin\u2010fold thickness. Fat\u2010free mass (FFM) and fat mass (FM) were measured by ADP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010three nutritional evaluations were performed in 28 infants with BA (13 boys, 44.4%). The median age was 20.7\u00a0weeks (IQR: 13\u201325.9). Based on the various anthropometry modalities, infants with BA were found to be malnourished on most of the visits; 63% had a MUAC\u2010Z score lower than \u22122\u00a0standard deviations. High serum bilirubin level predicted lower weight for age, length for age, and MUAC\u2010Z. Lower MUAC\u2010Z was associated with a higher PELD score. Neither FM mass nor FFM correlated with PELD or with serum bilirubin level. However, FM correlated with skin\u2010fold thickness\u2010Z and was low in most patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The majority of BA infants suffer from malnutrition as assessed by most anthropometrics modalities; low MUAC correlated best with disease severity and serum bilirubin level. Further studies are warranted to determine the contribution of FM measurement by ADP to the anthropometric assessment of infants with BA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14208","type":"journal-article","created":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T06:43:34Z","timestamp":1639982614000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Body composition correlates with laboratory parameters and disease severity in infants with biliary atresia"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6638-8392","authenticated-orcid":false,"given":"Luba","family":"Marderfeld","sequence":"first","affiliation":[{"name":"Institute of Gastroenterology, Nutrition and Liver Diseases Schneider Children\u2019s Medical Center of Israel  Petach Tikva Israel"},{"name":"Nutrition and Dietetics Department Schneider Children\u2019s Medical Center of Israel  Petach Tikva 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Medical Center of Israel  Petach Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari","family":"Silbermintz","sequence":"additional","affiliation":[{"name":"Institute of Gastroenterology, Nutrition and Liver Diseases Schneider Children\u2019s Medical Center of Israel  Petach Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irit","family":"Poraz","sequence":"additional","affiliation":[{"name":"Nutrition and Dietetics Department Schneider Children\u2019s Medical Center of Israel  Petach Tikva Israel"},{"name":"National Management Office Clalit Health Services Tel Aviv  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Reznik","sequence":"additional","affiliation":[{"name":"Institute of Gastroenterology, Nutrition and Liver Diseases Schneider Children\u2019s Medical Center of Israel  Petach Tikva Israel"},{"name":"Nutrition and Dietetics Department Schneider Children\u2019s Medical 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