{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:47:31Z","timestamp":1788306451825,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T00:00:00Z","timestamp":1665100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Refugee or asylum seekers (RAS) children are at increased risk of physical, developmental, and behavioral health issues. The aim of this study was to evaluate clinical and psychosocial outcomes of hematopoietic stem cell transplantation (HSCT) in RAS children and compare health\u2010related quality of life (HRQOL) to those of Turkish peers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study included patients who underwent HSCT aged 0\u201318\u2009years and completed 100\u2010day post\u2010transplant. The PedsQL 4.0 Generic Core Scale was used in children over 5\u2009years old to compare HRQOL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 166 RAS patients (M\/F: 106 \/60) underwent 174 HSCTs (six patients had two, and one had three HSCT) compared to 66 Turkish patients. The mean age of the patients in the RAS group was 7.8\u00a0\u00b1\u20094.9\u2009years and similar to controls. A total of 124 patients (75%) were from Syria, and 49 (25%) were from other countries in the Middle East and Africa. The cause of migration was war in 121 (74%) RAS patients. Complications of HSCT were no different between the groups. However, the rate of neutropenic sepsis was significantly higher in the RAS group (<jats:italic>p<\/jats:italic>\u00a0=\u20090.004). The total scores of HRQOL were not different between RAS and controls. In the RAS group, ratings of social functioning were lower in patients with consanguinity or non\u2010malignant disease or who had match\u2010related donors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Identifying areas of difficulty in subscales of HRQOL may help physicians to classify patients who need additional supportive care. Regular monitoring and supporting physical needs may result in better functional outcomes after HSCT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14397","type":"journal-article","created":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T03:40:01Z","timestamp":1665200401000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Hematopoietic stem cell transplantation activities and HRQOL of refugee or asylum seeker children in Turkey: A multicenter study"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8097-3950","authenticated-orcid":false,"given":"Dilek","family":"Gurlek Gokcebay","sequence":"first","affiliation":[{"name":"Pediatric Bone Marrow Transplantation Unit University of Health Sciences Ankara City Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serhan","family":"K\u00fcpeli","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pediatric Bone Marrow Transplantation Unit \u00c7ukurova University  Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orhan","family":"G\u00fcrsel","sequence":"additional","affiliation":[{"name":"Pediatric Bone Marrow Transplantation Unit University of Health Sciences G\u00fclhane Training and Research Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8316-3603","authenticated-orcid":false,"given":"Ozlem","family":"Arman Bilir","sequence":"additional","affiliation":[{"name":"Pediatric Bone Marrow Transplantation Unit University of Health Sciences Ankara City Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arzu","family":"Akyay","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pediatric Bone Marrow Transplantation Unit \u0130n\u00f6n\u00fc University  Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Pekpak","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pediatric Bone Marrow Transplantation Unit Gaziantep University  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinan","family":"Akbayram","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pediatric Bone Marrow Transplantation Unit Gaziantep University  Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yurday","family":"\u00d6nc\u00fcl","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pediatric Bone Marrow Transplantation Unit \u0130n\u00f6n\u00fc University  Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adalet","family":"Meral G\u00fcne\u015f","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pediatric Bone Marrow Transplantation Unit Uluda\u011f University  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serap","family":"Kirkiz","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pediatric Bone Marrow Transplantation Unit Gazi University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7489-2054","authenticated-orcid":false,"given":"Suar","family":"\u00c7ak\u0131 K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Pediatric Bone Marrow Transplantation Unit University of Health Sciences \u00dcmraniye Training and Research Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7666-8731","authenticated-orcid":false,"given":"\u0130kbal","family":"Ok Bozkaya","sequence":"additional","affiliation":[{"name":"Pediatric Bone Marrow Transplantation Unit University of Health Sciences Ankara City Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6857-0681","authenticated-orcid":false,"given":"Nam\u0131k Yasar","family":"Ozbek","sequence":"additional","affiliation":[{"name":"Pediatric Bone Marrow Transplantation Unit University of Health Sciences Ankara City Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10903-016-0405-3"},{"key":"e_1_2_9_3_1","first-page":"87","volume-title":"Advances in Pediatrics","author":"Kroening ALH","year":"2019"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2012.217"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCC.0000000000000339"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-020-0782-z"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(1999)83:12 <46::AID-IJC9>3.0.CO;2-C"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701853"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-197410000-00001"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(80)90380-0"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1367\/1539-4409(2003)003<0329:TPAAPP>2.0.CO;2"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-6712.2011.00889.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-007-9303-4"},{"key":"e_1_2_9_14_1","unstructured":"JW. V. No Title [Internet].PedsQL scoring algorithm: scoring the pediatric quality of life inventory.2017. Available from:https:\/\/www.pedsql.org\/sc\u0131re.html"},{"key":"e_1_2_9_15_1","unstructured":"Directorate General of Migration Management (DGMM) M. of I. Turkey. (2020).Migration statistics \u2010 temporary protection (April 2020). April RA 19 2020fromhttps:\/\/www.goc.gov.tr\/gecici\u2010koruma5638. No Title"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/03630269.2014.912661"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.27636"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199902000-00003"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.23133"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1703377"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.159.8.706"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701754"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.14397","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/petr.14397","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.14397","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T10:02:52Z","timestamp":1724839372000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.14397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,7]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1111\/petr.14397"],"URL":"https:\/\/doi.org\/10.1111\/petr.14397","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,7]]},"assertion":[{"value":"2022-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14397"}}