{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T12:07:04Z","timestamp":1770293224206,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cytomegalovirus (CMV) is a significant cause of morbidity among immunocompromised patients who have undergone kidney transplantation and is known to rarely induce collapsing focal segmental glomerulosclerosis (FSGS) among adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We present the first reported case of CMV\u2010induced collapsing FSGS in a pediatric patient after kidney transplant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our patient underwent a deceased donor kidney transplant due to end\u2010stage renal disease secondary to lupus nephritis. Approximately 4 months after transplantation, he developed signs of worsening kidney function in the setting of CMV viremia and was found to have collapsing features of FSGS on kidney transplant biopsy. He was managed with a prompt escalation of antiviral therapy along with a reduction of immunosuppression and recovered without significant complication. At follow\u2010up, he continued to have undetectable CMV titers, creatinine within normal limits, and no significant proteinuria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This report demonstrates CMV as a cause of collapsing FSGS and should be considered among pediatric transplant recipients who present with acute kidney injury, as should early assessment of APOL1 genetic status in both donor and recipient.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14535","type":"journal-article","created":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T05:08:31Z","timestamp":1683004111000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["<scp>CMV<\/scp>\u2010associated collapsing focal segmental glomerulosclerosis after kidney transplant in a pediatric patient"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2755-1262","authenticated-orcid":false,"given":"Madeline F. E.","family":"Parr","sequence":"first","affiliation":[{"name":"Division of Pediatric Nephrology, Department of Pediatrics Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center  Hackensack New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8003-6913","authenticated-orcid":false,"given":"Guillermo","family":"Hidalgo","sequence":"additional","affiliation":[{"name":"Division of Pediatric Nephrology, Department of Pediatrics Jersey Shore University Medical Center  Neptune New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5233-2814","authenticated-orcid":false,"given":"Michael J.","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Department of Transplant Surgery Hackensack University Medical Center  Hackensack New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0686-5457","authenticated-orcid":false,"given":"Ibrahim","family":"Batal","sequence":"additional","affiliation":[{"name":"Department of Pathology and Cell Biology Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5772-7708","authenticated-orcid":false,"given":"Kenneth V.","family":"Lieberman","sequence":"additional","affiliation":[{"name":"Division of Pediatric Nephrology, Department of Pediatrics Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center  Hackensack New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4513-8252","authenticated-orcid":false,"given":"Marlene R.","family":"Amoruso","sequence":"additional","affiliation":[{"name":"Department of Transplant Surgery Hackensack University Medical Center  Hackensack New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2716-8327","authenticated-orcid":false,"given":"Aryeh Z.","family":"Baer","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Disease, Department of Pediatrics Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center  Hackensack New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9103-6601","authenticated-orcid":false,"given":"Namrata G.","family":"Jain","sequence":"additional","affiliation":[{"name":"Division of Pediatric Nephrology, Department of Pediatrics Joseph M. Sanzari Children's Hospital at Hackensack University Medical Center  Hackensack New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.846173"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2018.06.024"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020050558"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfs059"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijn.IJN_65_19"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2018.10.14"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13512"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02834.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13528"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008030287"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013036"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12884"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijn.IJN_193_19"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1193032"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020060802"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2020.04.017"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020010079"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2018.05.008"},{"key":"e_1_2_7_20_1","unstructured":"APOL1 Long\u2010term Kidney Transplantation Outcomes Network (APOLLO).ClinicalTrials.govidentifier: NCT03615235. Updated April 11 2022. Accessed February 22 2023.https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03615235"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.3345\/kjp.2019.00388"},{"issue":"1","key":"e_1_2_7_22_1","first-page":"95","article-title":"Glomerulopat\u00eda colapsante asociada a virus BK en un ni\u00f1o con s\u00edndrome nefr\u00f3tico idiop\u00e1tico. Informe de un Caso [focal segmental glomerulosclerosis related to BK virus in a child with nephrotic syndrome. 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