{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T21:31:15Z","timestamp":1792186275425,"version":"4.4.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Pediatric Heart Transplant Society (PHTS) Registry was founded 30\u2009years ago as a collaborative effort among like\u2010minded providers of this novel life\u2010saving technique for children with end\u2010stage heart failure. In the intervening decades, the data from the Registry have provided invaluable knowledge to the field of pediatric heart transplantation. This report of the PHTS Registry provides a comprehensive look at the data, highlighting both the longevity of the registry and one unique aspect of the PHTS registry, allowing for exploration into children with single ventricle anatomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The PHTS database was queried from January 1, 1993 to December 31, 2019 to include pediatric (age\u2009&lt;\u200918\u2009years) patients listed for HT. For our analysis, we primarily analyzed patients by era. The early era was defined as children listed for HT from January 1, 1993 to December 31, 2004; middle era January 1, 2005 to December 31, 2009; and recent era January 1, 2010 to December 31, 2019. Outcomes after listing and transplant, including mortality and morbidities, are presented as unadjusted for risk, but compared across eras.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Since 1993, 11\u2009995 children were listed for heart transplant and entered into the PHTS Registry with 9755 listed during the study period. The majority of listings occurred within the most recent era. Waitlist survival improved over the decades as did posttransplant survival. Other notable changes over time include fewer patients experiencing allograft rejection or infection after transplant. Waitlist and posttransplant survival have changed dramatically in patients with single ventricle physiology and significantly differ by stage of single ventricle palliation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Key points from this PHTS Registry summary and focus on patients with single ventricle congenital heart disease in particular, include the changing landscape of candidates and recipients awaiting heart transplant. There is clear improvement in waitlist and transplant outcomes for children with both cardiomyopathy and congenital heart disease alike.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.14615","type":"journal-article","created":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T21:14:27Z","timestamp":1697058867000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Three decades of collaboration through the Pediatric Heart Transplant Society Registry: A journey through registry data with a highlight on children with single ventricle anatomy"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5491-8085","authenticated-orcid":false,"given":"Marc E.","family":"Richmond","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology, Morgan Stanley Children's Hospital of New York\u2010Presbyterian Columbia University Vagelos College of Physicians and Surgeons  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4051-2185","authenticated-orcid":false,"given":"Jennifer","family":"Conway","sequence":"additional","affiliation":[{"name":"Stollery Children's Hospital University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James K.","family":"Kirklin","sequence":"additional","affiliation":[{"name":"Kirklin Institute for Research in Surgical Outcomes University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan S.","family":"Cantor","sequence":"additional","affiliation":[{"name":"Kirklin Institute for Research in Surgical Outcomes University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devin A.","family":"Koehl","sequence":"additional","affiliation":[{"name":"Kirklin Institute for Research in Surgical Outcomes University of Alabama at Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwin K.","family":"Lal","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Primary Children's Hospital University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"McDonald","sequence":"additional","affiliation":[{"name":"Department of Cardiology Lucile Packard Children's Hospital Stanford  Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4746-7703","authenticated-orcid":false,"given":"Robert","family":"Gajarski","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Nationwide Children's Hospital Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly Y.","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Cardiology Children's Hospital of Philadelphia  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh K.","family":"Singh","sequence":"additional","affiliation":[{"name":"Hassenfeld Children's Hospital New York University Grossman School of Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Fenton","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital for Children NHS Foundation Trust and Cardiothoracic Transplant Unit  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3621-2246","authenticated-orcid":false,"given":"Alfred","family":"Asante\u2010Korang","sequence":"additional","affiliation":[{"name":"John Hopkins All Children's Hospital  St. Petersburg Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2540-5672","authenticated-orcid":false,"given":"Shahnawaz","family":"Amdani","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Cleveland Clinic Children's Hospital  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2341-0913","authenticated-orcid":false,"given":"Scott R.","family":"Auerbach","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Children's Hospital of Colorado University of Colorado Anschutz Medical Center  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4117-2282","authenticated-orcid":false,"given":"Melanie D.","family":"Everitt","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Children's Hospital of Colorado University of Colorado Anschutz Medical Center  Aurora 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