{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T09:46:15Z","timestamp":1780393575463,"version":"3.54.1"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,5]],"date-time":"2023-11-05T00:00:00Z","timestamp":1699142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pulmonary vein stenosis (PVS) is a rare pediatric condition associated with significant mortality and morbidity. PVS in patients following heart transplant (HT) has not yet been described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who had clinically significant PVS following a heart transplant during the time period of April 1, 2013 to April 30, 2023, at Seattle Children's Hospital were identified. Clinically significant PVS was defined as an atretic vein or a vein with a gradient of \u22654\u2009mmHg across at least one vein by echocardiogram or during cardiac catheterization. Patients who had a diagnosis of PVS prior to their transplant were excluded. A total of six patients were identified. We collected clinical data on these patients from their pre\u2010transplant course to their most recent status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age at HT was 7.5\u2009months (range 2\u201313\u2009months). The median time from HT to diagnosis of PVS was 3.5\u2009months (range 0.3\u201313\u2009months). At the last follow\u2010up, the patients had had two to five pulmonary vein interventions, and there were no mortalities. The donor\u2010to\u2010recipient weight and total cardiac volume (TCV) ratios were less than 2.0 in five of six of the patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PVS is a rare complication that is associated with patients who undergo HT during infancy. PVS develops soon after HT and screening should occur accordingly. Interestingly, high donor\u2010to\u2010recipient weight and TCV ratios are not necessarily associated with the development of PVS. Further work will need to be performed in order to determine the significance of PVS in post\u2010HT patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14636","type":"journal-article","created":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T07:12:59Z","timestamp":1699254779000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pulmonary vein stenosis in heart transplant patients"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5197-3416","authenticated-orcid":false,"given":"Connie","family":"Choi","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology Seattle Children's Hospital  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7587-7518","authenticated-orcid":false,"given":"Brian H.","family":"Morray","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Seattle Children's Hospital  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1572-4840","authenticated-orcid":false,"given":"Humera","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Seattle Children's Hospital  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9484-3006","authenticated-orcid":false,"given":"Mariska","family":"Kemna","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Seattle Children's Hospital  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.02.030"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2008.161356"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23679"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-0075"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/children8020128"},{"key":"e_1_2_10_7_1","article-title":"Alternative methods of virtual heart transplant \u2013 size matching for pediatric heart transplantation with and without donor medical images available","volume":"22","author":"Plasencia JD","year":"2018","journal-title":"Petr"},{"issue":"5","key":"e_1_2_10_8_1","article-title":"Management of Pediatric Pulmonary Vein Stenosis","volume":"1","author":"Callahan R","year":"2022","journal-title":"JSCAI"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/apc.apc_210_21"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2005.11.006"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2021.10.022"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2022.08.015"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.14636","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T09:44:08Z","timestamp":1725011048000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.14636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,5]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1111\/petr.14636"],"URL":"https:\/\/doi.org\/10.1111\/petr.14636","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,5]]},"assertion":[{"value":"2023-06-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14636"}}