{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T23:17:16Z","timestamp":1776467836304,"version":"3.51.2"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T00:00:00Z","timestamp":1703635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Pediatric heart transplant patients are routinely followed in dermatology clinics due to elevated risk of cutaneous malignancy. However, transplant patients may experience other, non\u2010cancer\u2010related dermatologic conditions including skin infections, inflammatory diseases, and drug eruptions that can cause significant medical and psychosocial comorbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective chart review of all pediatric heart transplant patients at Mayo Clinic Children's Center in Rochester, MN, was performed to determine the prevalence and spectrum of non\u2010cancer dermatologic conditions. Statistical analysis was conducted to look for associations between episodes of rejection and skin condition development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 65 patients who received heart transplants under the age of 18 and were followed at Mayo Clinic, 69% (<jats:italic>N<\/jats:italic>\u2009=\u200945) were diagnosed with at least one skin condition between transplant and the time of most recent follow\u2010up. Sixty\u2010two percent (<jats:italic>N<\/jats:italic>\u2009=\u200940) of patients were diagnosed with an inflammatory skin condition (most commonly acne and atopic dermatitis), 45% (<jats:italic>N<\/jats:italic>\u2009=\u200929) with an infectious skin condition (most commonly warts and dermatophyte infection), and 32% (<jats:italic>N<\/jats:italic>\u2009=\u200921) with a drug eruption (most commonly unspecified rash and urticaria). No association was found between presence of skin disease and number of rejection episodes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Non\u2010cancer dermatologic conditions are prevalent within pediatric heart transplant recipients and may directly impact their medical needs and quality of life. Dermatologist involvement in the care of post\u2010transplant pediatric patients is important, not only for cancer screening but also for diagnosis and treatment of common infectious and inflammatory skin conditions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14664","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T09:29:54Z","timestamp":1703669394000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence and spectrum of infectious and inflammatory dermatologic conditions occurring in pediatric heart transplant patients on a predominantly mTOR\u2010based immune suppressive regimen: A retrospective chart review"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6647-4159","authenticated-orcid":false,"given":"Ann","family":"Rydberg","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Psychology Mayo Clinic  Rochester 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