{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:44:10Z","timestamp":1753879450351,"version":"3.41.2"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:00:00Z","timestamp":1724976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Heart transplantation is often limited by the availability of transplantable donor heart and understanding of donor aspects that would influence transplant outcomes becomes important. In this study, donor characteristics and their impact on the outcomes of pediatric heart transplantations performed in South Korea were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed the medical records of patients less than 18\u2009years old who received heart transplantation between 2002 and 2022 in three tertiary hospitals located in South Korea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 139 cases were enrolled. One\u2010year mortality was 10.4% and total mortality was 33.8%. Forty\u2010nine recipients (35.3%) showed biopsy\u2010proven rejections and 20 (14.4%) showed cardiac allograft vasculopathy during mean follow\u2010up of 6.4\u2009\u00b1\u20094.9\u2009years. Six recipients (4.5%) showed left ventricle ejection fraction of less than 55% post\u2010transplantation. The mean age of the donors was 23.0\u2009\u00b1\u200915.4\u2009years. The most common cause of death of the donors was unspecified illness (46.4%). Donors with a history of diabetes, hypertension, smoking, and alcohol consumption were 0%, 3.1%, 32.1%, and 34.4%, respectively. Mean total ischemic time was 191.6\u2009\u00b1\u200972.7\u2009min, while total ischemic time was over 4\u2009h in 37 patients (26.6%). There were no significant relationship between donor factors and survival. However, donor's history of drinking or cardiopulmonary resuscitation was significantly associated with acute rejection and donor's age with cardiac allograft vasculopathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Donor factors did not show significant impact on post\u2010transplant survival but some factors were predictive of post\u2010transplant rejection and cardiac allograft vasculopathy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14847","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T10:59:45Z","timestamp":1725015585000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Donor Characteristics and Outcomes of Pediatric Heart Transplantation in South Korea"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0096-7364","authenticated-orcid":false,"given":"Susan\u00a0Taejung","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8398-6861","authenticated-orcid":false,"given":"Hyewon","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Asan Medical Center, University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1601-3685","authenticated-orcid":false,"given":"Jeong\u00a0Jin","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Asan Medical Center, University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3071-2661","authenticated-orcid":false,"given":"Sang\u00a0Yun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5768-5990","authenticated-orcid":false,"given":"Joonghyun","family":"Ahn","sequence":"additional","affiliation":[{"name":"Biomedical Statistics Center Institute of Data Science, Institute of Future Medicine, Samsung Medical Center  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9660-5949","authenticated-orcid":false,"given":"Jinyoung","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Samsung Medical Center, Sungkyunkwan University School of Medicine  Seoul 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