{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:36:06Z","timestamp":1791563766256,"version":"4.3.4"},"reference-count":44,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T00:00:00Z","timestamp":1726358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011775","name":"BC Children\u2019s Hospital Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011775","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000191","name":"Kidney Foundation of Canada","doi-asserted-by":"publisher","award":["2021IRG\u2010000001"],"award-info":[{"award-number":["2021IRG\u2010000001"]}],"id":[{"id":"10.13039\/501100000191","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Life with end\u2010stage organ failure is accompanied by an accumulation of traumatic medical or surgical experiences. Despite recovery after solid organ transplantation (SOT), many children and adolescents develop post\u2010traumatic stress symptoms (PTSS). PTSS remain underappreciated as a major comorbidity in SOT programs, despite their association with decreased quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective, cross\u2010sectional study of 86 pediatric SOT recipients (17 heart, 44 kidney, and 25 liver) to evaluate potential determinants of PTSS. Trauma symptoms were measured by the Child Trauma Screening Questionnaire (CTSQ). Demographic, baseline, and contemporaneous factors were tested for independent association with CTSQ scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median post\u2010transplant CTSQ score was 2 (IQR 1\u20134), and 22% were identified as high risk (score \u22655) for PTSD. Higher CTSQ scores were independently associated with the number of ICU days within the previous 12\u2009months, the number of medications (complexity), and involvement with foster care in the primary model (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> [adj.]\u2009=\u20090.26). The addition of the Family Impact Module improved the overall model (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> [adj.]\u2009=\u20090.33), wherein higher family functioning was independently associated with lower CTSQ scores. An exploratory analysis of pre\u2010transplant patients (<jats:italic>n<\/jats:italic>\u2009=\u200934) found a median pre\u2010transplant CTSQ of 2 (IQR 1\u20136), suggesting that PTSS are onset before transplant and persist afterward.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PTSS are highly prevalent in the SOT population. Risk factors include recent adverse medical experiences and complexity, whereas family stability may be protective. Additional research is needed to improve early ascertainment and support for patients at high risk of developing PTSS throughout their transplant journey.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14854","type":"journal-article","created":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T05:20:16Z","timestamp":1726464016000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Risk Factors of Post\u2010Traumatic Stress in Pediatric Solid Organ Transplant Recipients"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4290-3430","authenticated-orcid":false,"given":"Tatsuma","family":"Hind","sequence":"first","affiliation":[{"name":"Faculty of Medicine University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Robillard","sequence":"additional","affiliation":[{"name":"National Core for Neuroethics  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