{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T23:51:25Z","timestamp":1787356285241,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Much is reported regarding the detrimental effect of transfer to adult services for adolescent and young adult (AYA) kidney transplant (KT) recipients. However, AYA recipient age independent of time post\u2010KT, and not relating to transfer of care, is also a strong predictor of graft loss. We assessed KT graft survival if experiencing solely pediatric (PO) or adult services (AO) versus transfer from pediatric to adult services (PTA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort analysis of all first kidney transplant recipients between birth\u201424\u2009years of age, from 2000 to 2019 in New Zealand. Participant identification and data were obtained via the Australia and New Zealand Dialysis and Transplantation registry. Primary outcome was graft survival stratified by service type. Cox proportional hazard modeling assessed independent risk factors of graft loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred forty\u2010four children and AYA with a median follow\u2010up of 7.3\u2009years were included. Graft survival stratified by service provision group was not different. The incidence rate of graft loss was 37, 34, and 45 per 1000 persons per year for PO, PTA, and AO respectively. Crude age\u2010specific graft failure rates were highest for 22\u201324\u2010year\u2010olds with inferior outcomes starting from age 16, peaking at 24\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Older adolescence and young adulthood reflect a high\u2010risk period for KT loss. Transfer to adult services was not associated with worse graft survival compared to those experiencing either AO or PO alone. Improved models of care are needed to improve graft survival in this vulnerable population within New Zealand.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.14873","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T11:38:38Z","timestamp":1729510718000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Graft Loss in Pediatric and Young Adult Kidney Transplantation in New Zealand: Who Is at Greatest Risk and When?"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7780-9260","authenticated-orcid":false,"given":"N.","family":"Selvathesan","sequence":"first","affiliation":[{"name":"Starship Children's Hospital Te Whatu Ora Tamaki Makaurau  Auckland New Zealand"},{"name":"Division of Paediatric Nephrology, Department of Paediatrics The Hospital for Sick Children  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.\u00a0Y.","family":"Han","sequence":"additional","affiliation":[{"name":"Starship Children's Hospital Te Whatu Ora Tamaki Makaurau  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.\u00a0C.","family":"Palmer","sequence":"additional","affiliation":[{"name":"University of Otago  Christchurch New Zealand"},{"name":"Christchurch Hospital Te Whatu Ora Waitaha  Christchurch New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Dickens","sequence":"additional","affiliation":[{"name":"Starship Children's Hospital Te Whatu Ora Tamaki Makaurau  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Manley","sequence":"additional","affiliation":[{"name":"Auckland City Hospital Te Whatu Ora Tamaki Makaurau  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0463-0953","authenticated-orcid":false,"given":"C.","family":"Prestidge","sequence":"additional","affiliation":[{"name":"Starship Children's Hospital Te Whatu Ora Tamaki Makaurau  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,21]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"ANZDATA Registry. 43rd Report \u201cChapter\u00a012: Paediatric Patients with End Stage Kidney Disease Requiring Renal Replacement Therapy \u201dPublished Online 2020."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2012.09.024"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.8495"},{"key":"e_1_2_9_5_1","volume-title":"Kidney. Health Australia Youth Program\u2014State of the Nation Report","author":"Cornish S.","year":"2019"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-011-1980-0"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2005.00356.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.81.3.271"},{"key":"e_1_2_9_9_1","unstructured":"J.Atkinson P.Crampton andC.Salmond \u201cNZDep2018 Analysis of Census 2018 Variables \u201d2021Published Online."},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008030287"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u2010150\u20109\u2010200905050\u201000006"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.03.029"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.13597"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-020-02156-2"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31823411d7"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1526924816667952"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31821b2f4b"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.14873","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T06:39:49Z","timestamp":1730097589000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.14873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,21]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/petr.14873"],"URL":"https:\/\/doi.org\/10.1111\/petr.14873","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,21]]},"assertion":[{"value":"2024-05-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14873"}}