{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T17:53:00Z","timestamp":1766339580549,"version":"3.46.0"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pediatric Infectious Disease (PID) clinicians involved in solid organ transplantation often assess infection risk and mitigation strategies for donor organ offers. While some guidance is available, real\u2010life practice patterns have not been previously described.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We surveyed PID clinicians about organ acceptance and associated posttransplantation interventions using 12 fictitious pediatric case scenarios through 3 PID\u2010specific listservs. Descriptive statistics were employed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      48 (71.6%) of 67 ID respondents were involved in organ offer assessment. Agreement was strong (&gt;\u200980%) to accept (syphilis, severe acute respiratory syndrome coronavirus 2 [SARS\u2010CoV\u20102], MRSA,\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>E. coli<\/jats:italic>\n                      <\/jats:styled-content>\n                      , TB [liver], rhino\/enterovirus) or decline (undifferentiated encephalitis, TB [lung]) organs from these cases, while there was less agreement for cases with risk of coccidioidomycosis, Chagas disease, multi\u2010drug\u2010resistant\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Acinetobacter baumannii<\/jats:italic>\n                      <\/jats:styled-content>\n                      , and influenza. Less agreement was present for posttransplant monitoring and antimicrobial administration. Practice varied in testing and treatment for donors with SARS\u2010CoV\u20102 positive test, MRSA bacteremia, and Chagas disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>For many pediatric organ offer scenarios, agreement in donor acceptance was high; however, improved education based on currently available recommendations may enhance organ acceptance decision\u2010making. The variability in management highlights educational and research opportunities to optimize strategies to limit the impact of donor\u2010derived infections in pediatric organ recipients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70088","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T02:43:16Z","timestamp":1746672196000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Child Organ Offer Process (\n                    <scp>cOOPS<\/scp>\n                    ): Understanding Infectious Risk Assessment and Mitigation Strategies"],"prefix":"10.1111","volume":"29","author":[{"given":"Trinity","family":"Lee","sequence":"first","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center and University of Cincinnati  Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8653-4657","authenticated-orcid":false,"given":"Katya","family":"Prakash","sequence":"additional","affiliation":[{"name":"Institute of Human Virology University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9246-5662","authenticated-orcid":false,"given":"Hannah","family":"Bahakel","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center and University of Cincinnati  Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6011-2894","authenticated-orcid":false,"given":"Michael","family":"Green","sequence":"additional","affiliation":[{"name":"UPMC Children's Hospital Pittsburgh and University of Pittsburgh School of Medicine  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9230-7285","authenticated-orcid":false,"given":"Arnaud G.","family":"L'Huillier","sequence":"additional","affiliation":[{"name":"Pediatric Infectious Diseases Unit, Department of Women, Child and Adolescent Health University Hospitals of Geneva and Faculty of Medicine  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2556-0544","authenticated-orcid":false,"given":"Marian G.","family":"Michaels","sequence":"additional","affiliation":[{"name":"UPMC Children's Hospital Pittsburgh and University of Pittsburgh School of Medicine  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7959-1445","authenticated-orcid":false,"given":"William","family":"Otto","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center and University of Cincinnati  Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9464-5704","authenticated-orcid":false,"given":"Klara","family":"Posfay\u2010Barbe","sequence":"additional","affiliation":[{"name":"Pediatric Infectious Diseases Unit, Department of Women, Child and Adolescent Health University Hospitals of Geneva and Faculty of Medicine  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3452-0666","authenticated-orcid":false,"given":"Tanvi","family":"Sharma","sequence":"additional","affiliation":[{"name":"Boston Children's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9111-625X","authenticated-orcid":false,"given":"John W.","family":"Baddley","sequence":"additional","affiliation":[{"name":"Johns Hopkins School of Medicine  Baltimore Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5691-5221","authenticated-orcid":false,"given":"Lara","family":"Danziger\u2010Isakov","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center and University of Cincinnati  Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the OOPS 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