{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:36:35Z","timestamp":1792791395693,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Congenital heart disease (CHD) frequently coexists with noncardiac malformations. Among which, biliary atresia (BA) occurs in approximately 5%\u201315% of patients Despite this, outcomes of liver transplantation (LT) in patients with CHD and BA remain unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review of the Pediatric Health Information System (PHIS) database from January 1, 2004 to October 30, 2023. All patients who underwent LT and had a diagnosis of BA were included. Multiorgan transplants were excluded. International Classification of Diseases 9th and 10th editions were utilized to identify patients with a diagnosis consistent with CHD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 1677 patients were identified with 983 (59%) female, 811 (5%) white non\u2010Hispanic, and a median age at transplant of 11.6 (interquartile range [IQR]: 7.7\u201326.6) months. A CHD diagnosis was present in 83 (5%). Overall, the majority of transplants were performed in the CHD population in the modern era (2016\u20132023) (42\/83.51%). CHD had a longer median preoperative length of stay (LOS) compared to non\u2010CHD (1 [1.0\u201315.0] vs. 1 [0\u20136.0],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.031). No increased risk of in\u2010hospital mortality was evident (OR: 1.61, 95% CI: 0.37\u20136.95,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.519). On multivariable analysis, CHD was associated with a 29% (95% CI: 11.04\u201350.34) increase in LOS (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), 25% (95% CI: 6.98\u201346.47,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005) increase in postoperative LOS, and was not associated with increased risk for 30\u2010day readmission (OR: 1.14; CI: 0.53\u20132.45,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.736). Over a median follow\u2010up of 3.5\u2009years (IQR: 0.86\u20137.78) years, no difference in retransplantation rate was evident.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>LT in patients with CHD and BA is safe. Although patients with CHD display heightened utilization of in\u2010hospital resources, no discernible variance in long\u2010term outcomes was observed. However, additional research is imperative to comprehensively elucidate the influence of CHD on management decisions and outcomes throughout the liver transplant process.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70110","type":"journal-article","created":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T00:20:44Z","timestamp":1748650844000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Outcomes of Liver Transplantation in Patients With Congenital Heart Disease and Biliary Atresia. A Multicenter Analysis"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3731-5984","authenticated-orcid":false,"given":"Mario","family":"O'Connor","sequence":"first","affiliation":[{"name":"Department of Surgery and Perioperative Care Dell Medical School at the University of Texas, Austin  Austin TX USA"},{"name":"Department of Pediatrics Dell Medical School at the University of Texas, Austin  Austin TX USA"},{"name":"Texas Center for Pediatric and Congenital Heart Disease Dell Children's and UT Health, Texas, Austin  Austin TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel T.","family":"Adler","sequence":"additional","affiliation":[{"name":"Department of Surgery and Perioperative Care, Division of Transplant Surgery Dell Medical School at the University of Texas at Austin  Austin TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil M.","family":"Venardos","sequence":"additional","affiliation":[{"name":"Department of Surgery and Perioperative Care Dell Medical School at the University of Texas, Austin  Austin TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica S.","family":"Ponce\u2010Rivera","sequence":"additional","affiliation":[{"name":"Department of Surgery and Perioperative Care Dell Medical School at the University of Texas, Austin  Austin TX USA"},{"name":"Department of Pediatrics Dell Medical School at the University of Texas, Austin  Austin TX USA"},{"name":"Texas Center for Pediatric and Congenital Heart Disease Dell Children's and UT Health, Texas, Austin  Austin TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles D.","family":"Fraser","sequence":"additional","affiliation":[{"name":"Department of Surgery and Perioperative Care Dell Medical School at the University of Texas, Austin  Austin TX USA"},{"name":"Department of Pediatrics Dell Medical School at the University of Texas, Austin  Austin TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos M.","family":"Mery","sequence":"additional","affiliation":[{"name":"Department of Surgery and Perioperative Care Dell Medical School at the University of Texas, Austin  Austin TX USA"},{"name":"Department of Pediatrics Dell Medical School at the University of Texas, Austin  Austin TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Well","sequence":"additional","affiliation":[{"name":"Department of Surgery and Perioperative Care Dell Medical School at the University of Texas, Austin  Austin TX USA"},{"name":"Department of Pediatrics Dell Medical School at the University of Texas, Austin  Austin TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40472\u2010014\u20100036\u20103"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v13.i10.1351"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971\u20109261.158095"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v13.i4.33"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2016.04.003"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20103046.2007.00755.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild\u20102015\u2010309589"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.14598"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.017704"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14531"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.09.017"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9051456"},{"issue":"1","key":"e_1_2_10_14_1","first-page":"31","article-title":"Cardiovascular Dysfunction in Patients With Liver Cirrhosis","volume":"28","author":"Fede G.","year":"2015","journal-title":"Annals of Gastroenterology"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041\u20101345(02)02886\u20105"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i32.11131"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/TXD.0000000000001096"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.030821"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12563"},{"key":"e_1_2_10_20_1","unstructured":"R Core Team \u201cR: A Language and Environment for Statistical Computing. 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