{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:45:49Z","timestamp":1791297949904,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T00:00:00Z","timestamp":1755993600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Childhood overweight and obesity have been hypothesized to pose challenges in pediatric kidney transplantation due to potential complications and resultant worse outcomes. Herein, we aimed to determine if pediatric patients with an elevated body mass index (BMI) (&gt;\u200985th percentile) are at higher risk for short\u2010term complications following kidney transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Following a review of our transplant database (2010\u20132020), patients &gt;\u20092\u201318\u2009years were assigned to groups based on BMI percentiles at the time of surgery: normal (5th\u201385th percentile;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009120) and obese\/overweight (&gt;\u200985th percentile;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200960). Patients were matched using a 1\u2010to\u20102\u2010ratio nearest\u2010neighbor propensity score matching adjusting for underlying diagnosis, sex, and age. The primary outcome was postoperative complications classified according to Clavien\u2010Dindo, and secondary outcomes included postoperative creatinine and kidney graft rejection.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One hundred eighty patients (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009120 in the control and\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200960 in the overweight and obese group) were included. There was no significant difference in postoperative complications (72\/120 vs. 40\/60,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.42). We noted no difference in nadir creatinine (7\u2009days, [interquartile range (IQR) 1, 679] and 9\u2009days, [IQR 1, 690],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.11), postoperative creatinine levels at 3\u2010, 6\u2010, and 12\u2010months post\u2010transplantation, or rejection rates (8.4% and 8.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.99) between normal weighed and obese\/overweight patients. However, more overweight and obese patients required intraoperative blood transfusions (55% and 33.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) and longer hospital stays (18.0 [IQR 9, 133] and 15.0 [IQR 7, 49],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>It appears as though overweight and obese pediatric kidney transplant patients do not experience more postoperative complications. We propose that overweight and obesity should not be considered criteria to exclude pediatric patients from undergoing kidney transplantations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70163","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T06:46:44Z","timestamp":1756104404000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Overweight and Obesity in Pediatric Kidney Transplant Recipients Are Not Associated With Higher Risks of Early Postoperative Complications"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6887-0342","authenticated-orcid":false,"given":"Juliane","family":"Richter","sequence":"first","affiliation":[{"name":"Division of Urology, the Hospital for Sick Children and Department of Surgery University of Toronto  Toronto Ontario Canada"},{"name":"Department of Urology, Uro\u2010Oncology, Special Urological and Robot\u2010Assisted Surgery University Hospital of Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Doktor","sequence":"additional","affiliation":[{"name":"Division of General and Thoracic Surgery, the Hospital for Sick Children University of Toronto  Toronto Ontario Canada"},{"name":"Department of Pediatric Surgery University of Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0598-1824","authenticated-orcid":false,"given":"Mandy","family":"Rickard","sequence":"additional","affiliation":[{"name":"Division of Urology, the Hospital for Sick Children and Department of Surgery University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana Dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Division of Urology, the Hospital for Sick Children and Department of Surgery University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2509-0116","authenticated-orcid":false,"given":"Priyank","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation Sanjay Gandhi Postgraduate Institute of Renal Sciences  Lucknow India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5994-0799","authenticated-orcid":false,"given":"Chia Wei","family":"Teoh","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Pediatrics The Hospital for Sick Children  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashlene","family":"McKay","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Pediatrics The Hospital for Sick Children  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0964-9503","authenticated-orcid":false,"given":"Jin K.","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Urology, the Hospital for Sick Children and Department of Surgery University of Toronto  Toronto Ontario Canada"},{"name":"Division of Urology, Department of Surgery, Temerty Faculty of Medicine University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Chua","sequence":"additional","affiliation":[{"name":"Division of Urology, the Hospital for Sick Children and Department of Surgery University of Toronto  Toronto Ontario Canada"},{"name":"Division of Urology, Department of Surgery, Temerty Faculty of Medicine University of Toronto  Toronto Ontario Canada"},{"name":"Institute of Urology St. Luke's Medical Center  Quezon City 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