{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T03:21:09Z","timestamp":1769570469966,"version":"3.49.0"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K23DK133729"],"award-info":[{"award-number":["K23DK133729"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017245","name":"Hennepin Healthcare Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017245","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Changes to the calculation of the Kidney Donor Profile Index (KDPI) have lowered the KDPI of hepatitis C (HCV+) donor kidneys; therefore, increasing the proportion of pediatric\u2010prioritized kidneys that are HCV+. We aimed to study consent rates for HCV+ kidneys among pediatric kidney transplant candidates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified pediatric candidates waitlisted from 2019 to 2024 and excluded those who received a living donor transplant. We used logistic regression to identify candidate characteristics associated with HCV+ offer consent and Cox proportional hazards models to determine the association between HCV+ offer consent and the rate of deceased donor transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 3202 candidates included in the analysis, 124 (4%) consented to receive HCV+ deceased donor kidney offers, and 3077 (96%) did not. In adjusted logistic regression, higher candidate age (OR 1.09 per year, 95% CI 1.03\u20131.15,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002) and high PRA status (OR 2.76, 95% CI 1.42\u20135.37,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) were associated with a higher odds of consenting to receive HCV+ donor offers, whereas Hispanic ethnicity was associated with lower odds (OR 0.44, 95% CI 0.28\u20130.72,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001) of consenting to receive these offers. 2773 candidates (87%) received a transplant. There was no significant association between HCV+ donor offer consent status and transplant rate after adjusting for candidate characteristics. Only 1 received a kidney from a HCV+ donor.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Consent to receive HCV+ donor kidney offers was rare among pediatric kidney transplant candidates. Allocation changes that increase the proportion of pediatric\u2010prioritized kidneys that are HCV+ may decrease access to transplant for pediatric candidates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70167","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T07:07:09Z","timestamp":1757574429000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Consent to Receive Offers for Kidneys From Donors With Hepatitis C Among Pediatric Kidney Transplant Candidates in the United States"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1823-0117","authenticated-orcid":false,"given":"Syed Ali","family":"Husain","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Nephrology Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"Columbia University Renal Epidemiology Group  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9875-4087","authenticated-orcid":false,"given":"Lindsey M.","family":"Maclay","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Nephrology Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"Columbia University Renal Epidemiology Group  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5491-0278","authenticated-orcid":false,"given":"Miko","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Nephrology Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"Columbia University Renal Epidemiology Group  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7357-242X","authenticated-orcid":false,"given":"Sandra","family":"Amaral","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Pediatrics The Children's Hospital of Philadelphia  Philadelphia Pennsylvania USA"},{"name":"Department of Biostatistics and Epidemiology Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8913-6219","authenticated-orcid":false,"given":"John","family":"McAteer","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Pediatrics The Children's Hospital of Philadelphia  Philadelphia Pennsylvania USA"},{"name":"Division of Infectious Diseases The Children's Hospital of Philadelphia  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3307-8926","authenticated-orcid":false,"given":"Vishnu","family":"Potluri","sequence":"additional","affiliation":[{"name":"Renal\u2010Electrolyte and Hypertension Division Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5341-7286","authenticated-orcid":false,"given":"Jesse D.","family":"Schold","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Colorado \u2013 Anschutz Medical Campus  Aurora Colorado USA"},{"name":"Department of Epidemiology School of Public Health, University of Colorado \u2013 Anschutz Medical Campus  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5305-9685","authenticated-orcid":false,"given":"Sumit","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Nephrology Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"Columbia University Renal Epidemiology Group  New York New York USA"},{"name":"Department of Epidemiology Mailman School of Public Health, Columbia University  New York New York 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