{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T09:40:57Z","timestamp":1762940457621,"version":"3.45.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:00:00Z","timestamp":1759363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The rates of organ transplantation declined during the COVID\u201019 pandemic as donors testing positive for SARS\u2010CoV\u20102 on respiratory PCR were ineligible to donate. The implications of this practice are important for patients with limited donor pools, such as pediatric populations. Several case studies have demonstrated non\u2010inferior outcomes in adult patients receiving non\u2010pulmonary organ transplants from COVID\u2010positive adult donors. The feasibility and safety of such a transplant have yet to be established for donors under 1 year of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>We present two cases of non\u2010pulmonary, solid organ transplantation from donors under 1 year of age testing positive for COVID\u201019 on respiratory PCR in the absence of respiratory or systemic symptoms. The first patient was a 15\u2010month\u2010old with Wolcott\u2013Rallison Syndrome presenting with congenital diabetes and recurrent hepatitis. The patient underwent a combined liver\u2010pancreas transplant from an 8\u2010month\u2010old donor. Postoperatively, the recipient did not have any complications related to COVID\u201019 but experienced a self\u2010limited, transient respiratory distress. The second patient was a 5\u2010month\u2010old with methylmalonic acidemia experiencing recurrent metabolic crisis. The patient received a liver transplant from a 3\u2010month\u2010old donor. Immediate postoperative imaging revealed anastomotic thrombosis of the hepatic artery managed with arterial reconstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our case series is the first to establish the feasibility of non\u2010pulmonary solid organ transplants from a COVID\u2010positive donor under 1 year of age. This is also the first report of a successful combined liver\u2010pancreas transplant from an infant donor. Transplantation from donors with a positive SARS\u2010CoV\u20102 test may be feasible with adequate serologic testing and postoperative management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70196","type":"journal-article","created":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T04:30:38Z","timestamp":1759465838000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Using\n                    <scp>SARS<\/scp>\n                    \u2010\n                    <scp>CoV<\/scp>\n                    \u20102\u2010Positive Donors Under 1\u2009Year of Age: A Case Series of Successful Combined Liver\u2010Pancreas and Isolated Liver Pediatric Transplantation"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4636-6916","authenticated-orcid":false,"given":"Mckenna","family":"Brownell","sequence":"first","affiliation":[{"name":"Georgetown University School of Medicine  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piyush","family":"Gupta","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Moris","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udeme","family":"Ekong","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid","family":"Khan","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashlie","family":"Pavone","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Gondolesi","sequence":"additional","affiliation":[{"name":"Department of Urology Ichan School of Medicine at Mount Sinai  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumeet","family":"Gopwani","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megha","family":"Fitzpatrick","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cal","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Rumbo","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nada","family":"Yazigi","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Fishbein","sequence":"additional","affiliation":[{"name":"MedStar Georgetown Transplant Institute MedStar Georgetown University Hospital  Washington DC 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