{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T14:02:57Z","timestamp":1789653777597,"version":"4.0.0"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002377"],"award-info":[{"award-number":["UL1TR002377"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In pediatric kidney transplant recipients, native nephrectomy is sometimes performed to manage conditions such as polyuria, nephrotic syndrome, and recurrent infections. To minimize surgical morbidity, our center adopted a technique from the adult transplant program involving ligation of native ureters at the time of transplantation as an alternative to native nephrectomy in selected patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study describes our center's experience with pediatric patients who underwent ureteral ligation at transplantation between December 2008 and December 2022. Patient selection was based on clinical judgment rather than predefined criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixteen patients underwent ureteral ligation, with polyuria (12\/16) and proteinuria associated with focal segmental glomerulosclerosis (4\/16) as the primary indications. Ligation was unilateral in 5 patients and bilateral in 11. The average follow\u2010up was 5.7\u2009years. No operative complications directly attributable to ureteral ligation were observed, including native kidney pyelonephritis or need for reoperation. Although post\u2010transplant imaging often revealed hydronephrosis of the native kidneys, it had no clinical consequences. Late postoperative hypertension occurred in 31% of the ligation group compared to 47% of controls without ligation, while new\u2010onset hypertension was more common in the ligation group (18.8% vs. 5.1%). Pain scores postoperatively were comparable between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This technical report suggests that native ureteral ligation at pediatric kidney transplantation is feasible in selected patients but represents an empirical, non\u2010standard\u2010of\u2010care approach. Prospective comparative studies are needed to refine patient selection and assess long\u2010term outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70288","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:08:55Z","timestamp":1772996935000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Simultaneous Ureteral Ligation at the Time of Pediatric Kidney Transplantation: A Technical Report"],"prefix":"10.1111","volume":"30","author":[{"given":"Randi J.","family":"Ryan","sequence":"first","affiliation":[{"name":"The William J. von Liebig Center for Transplantation and Clinical Regeneration Mayo Clinic  Rochester Minnesota USA"},{"name":"Department of Surgery, Division of Transplant Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9956-8696","authenticated-orcid":false,"given":"Christian","family":"Hanna","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine, Division of Pediatric Nephrology and Hypertension Mayo Clinic  Rochester Minnesota USA"},{"name":"Department of Medicine, Division of Nephrology and Hypertension Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9318-2437","authenticated-orcid":false,"given":"Byron H.","family":"Smith","sequence":"additional","affiliation":[{"name":"The William J. von Liebig Center for Transplantation and Clinical Regeneration Mayo Clinic  Rochester Minnesota USA"},{"name":"Department of Quantitative Health Sciences Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salma","family":"Shaikhouni","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Nephrology and Hypertension Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla E.","family":"McDonough","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine, Division of Pediatric Nephrology and Hypertension Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9570-0506","authenticated-orcid":false,"given":"Hatem","family":"Amer","sequence":"additional","affiliation":[{"name":"The William J. von Liebig Center for Transplantation and Clinical Regeneration Mayo Clinic  Rochester Minnesota USA"},{"name":"Department of Medicine, Division of Nephrology and Hypertension Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5541-0085","authenticated-orcid":false,"given":"Carl H.","family":"Cramer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine, Division of Pediatric Nephrology and Hypertension Mayo Clinic  Rochester Minnesota USA"},{"name":"Department of Medicine, Division of Nephrology and Hypertension Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8687-9754","authenticated-orcid":false,"given":"Mikel","family":"Prieto","sequence":"additional","affiliation":[{"name":"The William J. von Liebig Center for Transplantation and Clinical Regeneration Mayo Clinic  Rochester Minnesota USA"},{"name":"Department of Surgery, Division of Transplant Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.04.078"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2011.12.008"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002093"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.13952"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467\u2010012\u20102115\u2010y"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20106143.2011.03721.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.13703"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0272\u20106386(12)80743\u20108"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2007.05.001"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2014.231"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017\u20101904"},{"issue":"1","key":"e_1_2_11_13_1","first-page":"9","article-title":"Pain in Children: Comparison of Assessment Scales","volume":"14","author":"Wong D. 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