{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T14:02:55Z","timestamp":1789653775880,"version":"4.0.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mucormycosis is a rare but devastating opportunistic fungal infection in immunocompromised hosts with particularly high morbidity and mortality in solid organ transplant recipients. Pediatric cases are exceedingly rare, and outcomes are often fatal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>\n                      We report a case of a 13\u2010year\u2010old girl on chronic peritoneal dialysis who received a deceased donor kidney transplant. She was at immunological risk due to a positive virtual crossmatch. Induction therapy included antithymocyte globulin and methylprednisolone, followed by a maintenance immunosuppressive regimen of prednisone, mycophenolate mofetil, and tacrolimus. Post\u2010transplant, she developed early graft dysfunction, anuria, and hemodynamic instability. A graft biopsy showed acute tubular necrosis and C4d positivity prompting plasma exchange for suspected antibody\u2010mediated rejection. Graft explant on day nine revealed angio\u2010invasive mucormycosis due to\n                      <jats:italic>Rhizopus arrhizus<\/jats:italic>\n                      . The rapid onset suggested the infection may have been acquired from the donor. Despite antifungal therapy, she suffered from recurrent arterial pseudoaneurysms in the surgical bed. She died 91\u2009days post\u2010transplant from a ruptured iliac artery mycotic aneurysm.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case highlights the challenges in diagnosing and managing mucormycosis in pediatric kidney transplant recipients. A high index of suspicion together with early recognition, aggressive surgical management, and appropriate antifungal treatment is essential. Donor derived fungal infections should be considered in cases of early onset disease. Unfortunately, outcomes remain poor.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70301","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T05:00:42Z","timestamp":1773723642000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fatal Renal Mucormycosis Following Pediatric Deceased Donor Kidney Transplantation in a High\u2010Risk Recipient: A Case Report"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4986-9036","authenticated-orcid":false,"given":"Cecil Steven","family":"Levy","sequence":"first","affiliation":[{"name":"Division of Paediatric Nephrology, Nelson Mandela Children's Hospital, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trusha","family":"Nana","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology and Infectious Diseases, Faculty of Health Sciences University of Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Perner","sequence":"additional","affiliation":[{"name":"National Health Laboratory Services, Faculty of Health Sciences University of Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zafar Ahmed","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Surgery, Charlotte Maxeke Johannesburg Academic Hospital, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel Lindokuhle","family":"Mahlase","sequence":"additional","affiliation":[{"name":"Division of Paediatric Nephrology, Nelson Mandela Children's Hospital, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nokukhanya","family":"Ngubane\u2010Mwandla","sequence":"additional","affiliation":[{"name":"Division of Paediatric Nephrology, Nelson Mandela Children's Hospital, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Peiser","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nelson Mandela Children's Hospital, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonya","family":"Kolman","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Nelson Mandela Children's Hospital, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Petersen","sequence":"additional","affiliation":[{"name":"Division of Paediatric Nephrology, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006408"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jim\u20102021\u2010001933"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12387"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2381-1"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.13172"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2018.07.006"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/pix041"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e3283630e4d"},{"key":"e_1_2_6_10_1","article-title":"Fungal Infection in Renal Transplant Patients","volume":"110","author":"Sheikh S. 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