{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T15:58:21Z","timestamp":1781279901784,"version":"3.54.1"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:00:00Z","timestamp":1778371200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2026,5]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n \n SOT recipients with prior\n Strongyloides stercoralis<\/jats:italic>\n infection risk hyperinfection post\u2010transplant. Risk\u2010based screening may miss at\u2010risk candidates as endemicity expands beyond classic regions.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Retrospective study of SOT candidates <\u200926\u2009years at Cincinnati Children's Hospital (2018\u20132024). Universal serology\u2010based screening was implemented in 2023.\n Seroprevalence<\/jats:italic>\n was estimated with exact 95% CIs; seropositive and seronegative patients were compared on demographic and exposure characteristics.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n 178 patients were screened. Seroprevalence was 3.4% (6\/178; 95% CI 1.2%\u20137.2%), similar across pre\u2010universal (4.3%) and universal (2.9%) screening periods. Seropositive patients were older (15.7 vs. 8.5\u2009years;\n p<\/jats:italic>\n \u2009=\u20090.015) but did not differ on Appalachian exposure, international travel, eosinophilia, or other classical risk factors. Half of seropositive patients lacked any identifiable exposure criterion. All were asymptomatic and treated with two\u2010dose ivermectin.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n S. stercoralis<\/jats:italic>\n seroprevalence was low but clinically significant in this non\u2010endemic pediatric SOT cohort. Risk\u2010based screening would have missed a meaningful proportion of seropositive candidates, supporting consideration of universal screening and underscoring the need for broader regional seroprevalence data.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/petr.70334","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T05:38:49Z","timestamp":1778477929000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seroprevalence of\n Strongyloides stercoralis<\/i>\n Among Pediatric Solid Organ Transplant Candidates at a Tertiary Pediatric Medical Center in the United States"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7959-1445","authenticated-orcid":false,"given":"William","family":"Otto","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlin","family":"Brammer","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Liu","sequence":"additional","affiliation":[{"name":"University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Mysorewala","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant","family":"Paulsen","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5691-5221","authenticated-orcid":false,"given":"Lara","family":"Danziger\u2010Isakov","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilary","family":"Miller\u2010Handley","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"},{"name":"Department of Medicine University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572\u2010023\u201000490\u2010x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00033\u201023"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13618"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.09.002"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.14039"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.14\u20100310"},{"key":"e_1_2_8_9_1","first-page":"843","article-title":"Notes From the Field: Strongyloidiasis in a Rural Setting\u2010Southeastern Kentucky, 2013","volume":"62","author":"Centers for Disease Control and Prevention","year":"2013","journal-title":"MMWR. Morbidity and Mortality Weekly Report"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2708.204318"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.20\u20100026"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.70334","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/petr.70334","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.70334","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T14:57:49Z","timestamp":1781276269000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.70334"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1111\/petr.70334"],"URL":"https:\/\/doi.org\/10.1111\/petr.70334","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"2025-11-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70334"}}