{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:07:00Z","timestamp":1788858420808,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Children with end\u2010stage dilated cardiomyopathy (DCM) usually undergo heart transplantation or a short\u2010term bridge with a ventricular assist device. Heartmate 3 (HM3) may represent an appealing longer\u2010term option, though pediatric data are limited. We analyzed two clinical registries and hypothesized that adolescents with DCM treated with either HM3 or transplant would present similar survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Pedimacs and Pediatric Heart Transplant Society registries were queried for DCM patients ages 10\u201318\u2009years treated with HM3 or transplant, between 2017 and 2022. Mortality and adverse events were reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ninety HM3 and 306 transplant patients were reported within the respective registries. There was a higher proportion of Black patients in the HM3 cohort (40% vs. 30% in the transplant cohort,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03). Twelve\u2010 and 36\u2010month survival rates were both 94.4% for HM3 patients and were 99.3% and 95.6% for transplant patients. In the HM3 group, there were 66 transplants (median time of 2.8\u2009months), 3 late explants for recovery, and 3 early deaths. Conditional 1\u2010year survival for HM3 and transplant was 100% and 96.3%, respectively, at 3\u2009years. In the HM3 group, bleeding, stroke, and device malfunction rates were low at \u20090.1 events per patient per year.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Adolescents with DCM treated with either HM3 or transplant had excellent 3\u2010year outcomes, though many HM3 pediatric patients are transplanted early after device placement. Safely supporting this group of patients for an extended duration with HM3 has implications for delaying\/avoiding transplantation, longer\u2010term patient survival, and donor organ availability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70374","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T12:05:53Z","timestamp":1782216353000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparing Outcomes of Heartmate 3 and Heart Transplantation in Older Children With Dilated Cardiomyopathy\u2014Can Transplantation be Delayed or Avoided?"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5460-9079","authenticated-orcid":false,"given":"Waldemar F.","family":"Carlo","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Alabama  Birmingham USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4032-044X","authenticated-orcid":false,"given":"Luz A.","family":"Padilla","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Alabama  Birmingham USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7861-3267","authenticated-orcid":false,"given":"James K.","family":"Kirklin","sequence":"additional","affiliation":[{"name":"Kirklin Solutions  Birmingham USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3102-2638","authenticated-orcid":false,"given":"Ryan S.","family":"Cantor","sequence":"additional","affiliation":[{"name":"Kirklin Solutions  Birmingham USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3244-0970","authenticated-orcid":false,"given":"Devin","family":"Koehl","sequence":"additional","affiliation":[{"name":"Kirklin Solutions  Birmingham USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9916-929X","authenticated-orcid":false,"given":"Jeffrey P.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics University of Florida  Gainesville USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2540-5672","authenticated-orcid":false,"given":"Shahnawaz","family":"Amdani","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cleveland Clinic Children's  Cleveland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0021-1097","authenticated-orcid":false,"given":"Kathryn","family":"Chatfield","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado Anschutz Medical Campus  Aurora USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5114-8641","authenticated-orcid":false,"given":"Manan","family":"Desai","sequence":"additional","affiliation":[{"name":"Children's National Hospital  Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5399-0104","authenticated-orcid":false,"given":"Gabrielle","family":"Vaughn","sequence":"additional","affiliation":[{"name":"Rady Children's Hospital  San Diego USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5071-6983","authenticated-orcid":false,"given":"Catherine M.","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Children's Hospital of Philadelphia  Philadelphia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1931-4304","authenticated-orcid":false,"given":"Katerina","family":"Boucek","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina  Charleston USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1796-9171","authenticated-orcid":false,"given":"Katheryn","family":"Gambetta","sequence":"additional","affiliation":[{"name":"Lurie Children's Hospital  Chicago USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7512-1777","authenticated-orcid":false,"given":"David L. 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