{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T11:22:58Z","timestamp":1787743378611,"version":"build-2784847793"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Survival in pediatric liver transplantation (PLT) has significantly improved in infants under 1\u2009year, but &lt;\u200910\u2009kg and &lt;\u20096\u2009months continue to have poor outcomes with a paucity of information on ultra\u2010low weight (ULW) infants (&lt;\u20095\u2009kg). We compared intraoperative vasopressor use in &lt;\u20095\u2009kg versus 5\u2013&lt;\u20099.9\u2009kg PLT recipients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a single\u2010center retrospective review of all PLT recipients &lt;\u200910\u2009kg at time of transplant from 2009 to 2022, excluding multi\u2010organ transplantation. We collected data on demographics, diagnosis, intraoperative vasoactive infusions, blood loss and requirements, and abdominal closure timing. Outcomes data include total mechanical ventilation, intensive care and hospital length of stay days, 1\u2010year patient and graft survival and thrombotic complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      ULW &lt;\u20095\u2009kg and 5\u20139.9\u2009kg patients showed average weight of 4.53 versus 7.30\u2009kg (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value &lt;\u20090.0001) and average age of transplant 3.36 versus 7.90\u2009months (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value 0.0002). The most common etiology of liver disease for ULW versus 5\u20139.9\u2009kg was neonatal acute liver failure (3 of 5) versus biliary atresia (41 of 63). No significant difference in anhepatic time, abdominal closure, blood products transfused\/kg, estimated blood loss\/kg was noted. Total days of mechanical ventilation, ICU and hospital LOS were similar between groups. ULW trends toward higher doses of vasopressors during PLT, most notably at end of case compared to 5\u20139.9\u2009kg (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.06). Overall, 1\u2010year graft and patient survival were 91% and 94%, respectively. HAT and PVT did not appear to be associated with VIS by phase of surgery, but PVT occurred relatively more in the &lt;\u20095\u2009kg group (2 vs. 4) and HAT in the 5\u20139.9\u2009kg group (0 vs. 3).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Results show etiology of liver failure differs and &lt;\u20095\u2009kg trends to an increased amount of vasopressor use, especially at end of case, suggesting more hemodynamic instability requiring support; however, this did not correlate with measured hospital metrics. Split graft PLT recipients have more blood loss and require more transfusions. PVT was observed more in the &lt;\u20095\u2009kg cohort. Etiology, not just size or early age, may contribute to the higher and sustained pressor requirements and possible PVT risk in ULW infants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70420","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T08:15:46Z","timestamp":1786004146000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultra\u2010Low Weight &lt;\u20095 Versus 5\u20139.9\u2010kg Pediatric Liver Transplant Recipients: Characteristics and Intraoperative Vasopressor Comparisons"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9032-8282","authenticated-orcid":false,"given":"Lori A.","family":"Aronson","sequence":"first","affiliation":[{"name":"Cincinnati Children's Hospital and Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0443-1660","authenticated-orcid":false,"given":"Kim My","family":"Li","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital and Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9802-5948","authenticated-orcid":false,"given":"Alexander J.","family":"Bondoc","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital and Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5732-5832","authenticated-orcid":false,"given":"Stephen","family":"Hartman","sequence":"additional","affiliation":[{"name":"University of Cincinnati Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa","family":"Stetson","sequence":"additional","affiliation":[{"name":"University of Cincinnati Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1527-814X","authenticated-orcid":false,"given":"Cheryl","family":"Hartzell","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital and Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6573-1611","authenticated-orcid":false,"given":"Nicolas","family":"Noriega","sequence":"additional","affiliation":[{"name":"University of Cincinnati Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2345-3726","authenticated-orcid":false,"given":"Lili","family":"Ding","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital and Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9006-5552","authenticated-orcid":false,"given":"Jiwon","family":"Lee","sequence":"additional","affiliation":[{"name":"University of Cincinnati Medical Center  Cincinnati Ohio 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