{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:05:35Z","timestamp":1790381135744,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Biological parental donations provide the best option for many pediatric recipients, yielding unique immunological benefits that may enable minimization of immunosuppression in transplanted children. However, living related maternal donation in the postpartum period may introduce an increased risk of donor complications due to the physiological changes of pregnancy and childbirth, and the optimal timing of postpartum living donation is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using US national registry data, we characterized donor and recipient outcomes for pediatric living donor liver transplants performed between 2004 and 2022 where a biological mother donated to a child \u2264\u200924\u2009months old.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Our study population included 256 donor\u2010recipient pairs, with biliary atresia representing the most common indication for transplantation (68.0%). Donors had a median [IQR] age of 30 [25, 34] years, and the median [IQR] time from birth to donation was 9.0 [6.8, 13.0] months. 6.3% of donors experienced a biliary or other complication. When stratifying by donors who donated \u2264\u20096 vs. &gt;\u20096\u2009months postpartum, we found no significant differences in donor complications or readmission. Stratified analyses were also comparable for recipient mortality, graft survival, and rejection\u2010free survival. Donors \u2264\u20096\u2009months postpartum (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200964) were more likely to experience reoperation than mothers who donated &gt;\u20096\u2009months postpartum (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009192) (6.2% vs. 1.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>While maternal living donor liver transplantation is safe for most donors, there is a higher risk of reoperation when donation is performed \u2264\u20096\u2009months postpartum. Surgeons should be aware that these donors are a higher risk population, requiring discussion upon consent and warranting close post\u2010operative monitoring.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70449","type":"journal-article","created":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T05:30:51Z","timestamp":1787981451000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Biological Mother\u2010To\u2010Child Living Donor Liver Transplantation: Early Vs. Late Postpartum Donation"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8165-525X","authenticated-orcid":false,"given":"Jacqueline I.","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Surgery Transplant Institute, NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5925-9925","authenticated-orcid":false,"given":"Suhani S.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Surgery Transplant Institute, NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0617-4015","authenticated-orcid":false,"given":"Lauren M.","family":"Kucirka","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology The University of North Carolina  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2585-0154","authenticated-orcid":false,"given":"Shivani S.","family":"Bisen","sequence":"additional","affiliation":[{"name":"Department of Surgery Transplant Institute, NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8697-4863","authenticated-orcid":false,"given":"Jennifer","family":"Vittorio","sequence":"additional","affiliation":[{"name":"Department of Pediatrics NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4894-2024","authenticated-orcid":false,"given":"Adam","family":"Griesemer","sequence":"additional","affiliation":[{"name":"Department of Surgery Transplant Institute, NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1924-4801","authenticated-orcid":false,"given":"Dorry L.","family":"Segev","sequence":"additional","affiliation":[{"name":"Department of Surgery Transplant Institute, NYU Langone Health  New York New York USA"},{"name":"Scientific Registry of Transplant Recipients  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4484-6190","authenticated-orcid":false,"given":"AnnMarie","family":"Liapakis","sequence":"additional","affiliation":[{"name":"Department of Medicine NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5288-5125","authenticated-orcid":false,"given":"Allan B.","family":"Massie","sequence":"additional","affiliation":[{"name":"Department of Surgery Transplant Institute, NYU Langone Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajt.2023.02.006"},{"key":"e_1_2_11_3_1","volume-title":"Organ Procurement and Transplantation Network National Data"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.140.5.465"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20106143.2006.01626.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.25499"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.2014"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20106143.2011.03895.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/tri.12273"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001094"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002110"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajt.2025.01.022"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i32.11062"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24605"},{"key":"e_1_2_11_15_1","volume-title":"StatPearls","author":"Chauhan G.","year":"2023"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000183540.69405.90"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2014.00065"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198908313210919"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20103046.2004.00187.x"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12777"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.14197"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181aaccb0"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.09.004"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2014.03.020"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation\u20102009.1.277"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15674"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16494"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16978"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajt.2024.01.014"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20288"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24433"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.70449","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/petr.70449","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.70449","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:52:57Z","timestamp":1790380377000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.70449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,28]]},"references-count":30,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/petr.70449"],"URL":"https:\/\/doi.org\/10.1111\/petr.70449","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,28]]},"assertion":[{"value":"2025-02-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70449"}}