{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T05:48:29Z","timestamp":1791611309304,"version":"4.3.4"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Central venous catheters (CVCs) are essential during pediatric hematopoietic stem cell transplantation (HSCT), but prolonged retention exposes patients to infection, thrombosis, device complications, caregiver burden, and ongoing maintenance costs. Routine maintenance costs and variation in posttransplant CVC care have not been well characterized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a descriptive mixed\u2010methods study combining direct observation of CVC maintenance at Cincinnati Children's Hospital Medical Center with a cross\u2010sectional survey of Engraft Learning Health Network centers. Between January and March 2025, 15 dressing changes and 10 cap changes, predominantly on double\u2010lumen tunneled CVCs, were observed. Procedure time, staffing, supplies, and local labor and supply costs were evaluated using itemized micro\u2010costing. Fifteen respondents representing 10 Engraft centers reported routine dressing\u2010 and cap\u2010change practices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Dressing\u2010change practices were consistent, with all centers reporting changes every 7\u2009days or sooner when dressing integrity was compromised. Cap\u2010change intervals varied from daily to every 7\u2009days. Dressing changes required a mean of 16.5\u2009min and cost $55.25 in labor and supplies. Cap changes cost $24.08, and daily flushing cost $13.70. Estimated routine maintenance costs were $675\u2013$728 per patient\u2010month.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Routine CVC maintenance after pediatric HSCT is resource intensive and varies across centers. These findings support standardization of maintenance practices and timely CVC removal when central access is no longer clinically necessary.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/petr.70493","type":"journal-article","created":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T04:49:41Z","timestamp":1791607781000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Routine Central Venous Catheter Maintenance After Pediatric Hematopoietic Stem Cell Transplant: Direct Cost Observations From a Single Center and Practice Variation Across Engraft Centers"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8490-6912","authenticated-orcid":false,"given":"Steffani","family":"Maier","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio USA"},{"name":"Division of Bone Marrow Transplantation and Immune Deficiency Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4001-9203","authenticated-orcid":false,"given":"Christopher E.","family":"Dandoy","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio USA"},{"name":"Division of Bone Marrow Transplantation and Immune Deficiency Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney","family":"Culbertson","sequence":"additional","affiliation":[{"name":"Akron Children's Hospital  Akron Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor","family":"Fitch","sequence":"additional","affiliation":[{"name":"Aflac Cancer and Blood Disorders Center Children's Healthcare of Atlanta, and Emory University  Atlanta Georgia 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