{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T06:39:33Z","timestamp":1789799973838,"version":"4.0.1"},"reference-count":61,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T00:00:00Z","timestamp":1548288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Public Health Nursing"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Multidrug\u2010resistant tuberculosis (MDR\u2010TB) brings major challenges to the health care workers (HCWs). This study is to determine the risk factors for MDR\u2010TB, latent tuberculosis infection (LTBI), and tuberculosis (TB) disease among HCWs in China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A meta\u2010analysis was conducted to evaluate the risk factors for MDR\u2010TB, LTBI, and TB disease among HCWs using a random\u2010effects model, and the pooled odds ratios (ORs) with 95% confidence interval (CI) were used as effect indicators.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 46 eligible studies and found eight factors were associated with MDR. The ORs with 95% CI are migrant population 1.96 (95% CI, 1.50\u20132.57), low family income 2.23 (95% CI, 1.74\u20132.85), retreatment 7.22 (95% CI, 5.63\u20139.26), anti\u2010TB treatment history 5.65 (95% CI, 4.80\u20136.65), multiple episodes of treatment 3.28 (95% CI, 2.60\u20134.13), adverse reactions 3.48 (95% CI, 2.54\u20134.76), interrupted treatment 3.18 (95% CI, 2.60\u20133.89), and lung cavities 1.42 (95% CI, 1.14\u20131.77). Work duration as a HCW for 5\u00a0years and above increased the risk of LTBI and TB. HCWs aged 30\u00a0years and above were more susceptible to TB (OR\u00a0=\u00a01.70, 95% CI: 1.37\u20132.09).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The risk factors for MDR\u2010TB in China are possibly migrant population, low family income, retreatment, anti\u2010TB treatment history, adverse reactions, interrupted treatment, and lung cavities. Longer work duration and greater age are risk factors for LTBI and TB among HCWs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phn.12582","type":"journal-article","created":{"date-parts":[[2019,1,25]],"date-time":"2019-01-25T03:07:38Z","timestamp":1548385658000},"page":"257-269","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Risk factors of multidrug\u2010resistant tuberculosis in China: A meta\u2010analysis"],"prefix":"10.1111","volume":"36","author":[{"given":"Mei","family":"Feng","sequence":"first","affiliation":[{"name":"Department of Hyperbaric Oxygen Guizhou Provincial People's Hospital Guiyang Guizhou Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YuanGao","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Urology People's Hospital Affiliated to Guizhou Medical University Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XiangYan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Guizhou Provincial People's Hospital Guiyang Guizhou Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chongqing Public Health Center Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ShiGuang","family":"Lei","sequence":"additional","affiliation":[{"name":"Guizhou Provincial Center for Disease Control and Prevention Guiyang Guizhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JinLan","family":"Li","sequence":"additional","affiliation":[{"name":"Guizhou Provincial Center for Disease Control and Prevention Institute for Tuberculosis Control and Prevention  Guiyang Guizhou Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Yuan","sequence":"additional","affiliation":[{"name":"Guizhou Provincial Center for Disease Control and Prevention Institute for Tuberculosis Control and Prevention  Guiyang Guizhou Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"QunFeng","family":"Song","sequence":"additional","affiliation":[{"name":"Guizhou Provincial Center for Disease Control and Prevention Institute for Tuberculosis Control and Prevention  Guiyang Guizhou Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4666-9319","authenticated-orcid":false,"given":"JinHong","family":"Xu","sequence":"additional","affiliation":[{"name":"Guizhou Provincial Center for Disease Control and Prevention Institute for Tuberculosis Control and Prevention  Guiyang Guizhou Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmyco.2012.07.007"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.11.0574"},{"key":"e_1_2_7_4_1","first-page":"101","article-title":"An analysis on screening effect and risk factor of multidrug tuberculosis","volume":"1","author":"Chen L.","year":"2012","journal-title":"Zhong Guo Fang Lao Xie Hui Ke Pu Jiao Wei Yuan Hui Mo He Xue Shu Hui Yi"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2013.06.006"},{"key":"e_1_2_7_6_1","first-page":"47","article-title":"The study of the risk factors of multidrug resistance in patients with tuberculosis","volume":"38","author":"Chen S. 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