{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T08:48:11Z","timestamp":1765961291981,"version":"3.40.5"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T00:00:00Z","timestamp":1599436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Ruth L. Kirschstein National Research Service Award\/National Institute of Health (NIH)\/Nursing Research","award":["T32 NR007077"],"award-info":[{"award-number":["T32 NR007077"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Public Health Nursing"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To examine socio\u2010demographic and health\u2010related factors associated with latent tuberculosis infection (LTBI) treatment refusal, non\u2010initiation, and non\u2010completion among a cohort of Vietnamese immigrants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>This is a retrospective cohort study in which LTBI charts were reviewed at a public health clinic in Orange County, California between January 2010 and August 2011.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample<\/jats:title><jats:p>Altogether, 474 patient charts with documented LTBI treatment were reviewed for patients who met the inclusion criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements<\/jats:title><jats:p>Univariate and multivariate analyses were used to identify socio\u2010demographic and health\u2010related factors associated with LTBI treatment refusal, non\u2010initiation, and non\u2010completion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 474 charts reviewed, 171(36.1%) patients refused LTBI treatment and 21(6.9%) accepted but did not initiate. Of the 282 that started treatment, 62 (22.0%) did not complete the regimen prescribed. The primary barrier documented for treatment refusal and non\u2010completion was concern about medication side effects. Other barriers to treatment non\u2010completion include transportation issues and conflicts with travel plans or work schedules.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Community and public health nurses working with the Vietnamese immigrant population can play a vital role in improving patients\u2019 LTBI treatment acceptance, initiation, and completion. A proactive approach to addressing barriers and potential medication side effects can improve overall treatment success.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phn.12798","type":"journal-article","created":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T07:44:17Z","timestamp":1599637457000},"page":"846-853","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Non\u2010completion of latent tuberculosis infection treatment among Vietnamese immigrants in Southern California: A retrospective study"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6905-6545","authenticated-orcid":false,"given":"Fayette","family":"Nguyen Truax","sequence":"first","affiliation":[{"name":"School of Nursing Loma Linda University Loma Linda CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1338-2231","authenticated-orcid":false,"given":"Donald","family":"Morisky","sequence":"additional","affiliation":[{"name":"School of Public Health University of California, Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Low","sequence":"additional","affiliation":[{"name":"County of Orange Health Care Agency Santa Ana CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Carson","sequence":"additional","affiliation":[{"name":"County of Orange Health Care Agency Santa Ana CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haimanot","family":"Girma","sequence":"additional","affiliation":[{"name":"County of Orange Health Care Agency Santa Ana CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4979-6620","authenticated-orcid":false,"given":"Adeline","family":"Nyamathi","sequence":"additional","affiliation":[{"name":"Sue and Bill Gross School of Nursing University of California, Irvine Irvine CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s40471-016-0076-6","article-title":"Getting to zero. 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