{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T09:22:20Z","timestamp":1788340940760,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Public Health Nursing"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to determine the seroprevalence of hepatitis B, C, and D in Mardin, T\u00fcrkiye, identify at\u2010risk populations, and evaluate the effect of the hepatitis B vaccination program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>HBsAg, anti\u2010HBs, anti\u2010HBc IgG, anti\u2010HCV and anti\u2010HDV results were analysed retrospectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the 30430 patients (60.2% female) tested, seropositivity rates were 2.1% for HBsAg, 55.2% for anti\u2010HBs, 27.8% for anti\u2010HBc IgG, and 0.14% for anti\u2010HCV; of HBsAg\u2010positive patients, 6.1% were anti\u2010HDV positive. After adjusting for Mardin's age distribution, the age\u2010weighted rates were 1.48%, 56.3%, 15.9%, 0.12%, and 6.2% (for anti\u2010HDV in adults). Those born after 1998 (aged \u2264 26), when hepatitis B vaccination began nationally, had significantly lower HBsAg (0.3%\u00a0vs. 2.8%) and anti\u2010HBc IgG (2.5%\u00a0vs. 36.6%) positivity, and higher anti\u2010HBs (59.1%\u00a0vs. 53.4%) positivity, than older individuals (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). In a subgroup of 2703 with all hepatitis B markers, vaccine\u2010induced immunity was more frequent in those aged \u2264 26 years (55.4%\u00a0vs. 22.0%), while natural immunity (1.5%\u00a0vs. 26.7%) and chronic infection (0.6%\u00a0vs. 4.9%) were more common in those aged \u2265 27 years (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This large\u2010scale survey in Mardin shows that hepatitis B vaccination reduced prevalence, highlighting the need for targeted screening and public health nursing interventions in older adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/phn.70148","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T09:36:39Z","timestamp":1782898599000},"page":"1152-1158","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Determination of Seroprevalence of Chronic Hepatitis B, C and D: A Cross\u2010Sectional Study From T\u00fcrkiye"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7198-4324","authenticated-orcid":false,"given":"Muhammet Salih","family":"Tarhan","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology Mardin Training and Research Hospital  Mardin T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.15256"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.BJID.2012.06.003"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/S12985\u2010017\u20100845\u2010Y"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00281\u2010018\u20100727\u20104"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2025.2452955"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/JOURNAL.PONE.0110143"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(10)61931\u20109"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/LIV.15467"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S366255"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.5578\/MB.20249762"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.46310\/TJIM.1215109"},{"key":"e_1_2_9_13_1","doi-asserted-by":"crossref","unstructured":"Pattyn J. G.Hendrickx A.Vorsters andP.Van Damme.2021. \u201cHepatitis B Vaccines.\u201dThe Journal of Infectious Diseases224 no. 12 Suppl 2:S343\u2013S351.https:\/\/doi.org\/10.1093\/INFDIS\/JIAA668.","DOI":"10.1093\/infdis\/jiaa668"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/IJMS23010500"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.36519\/IDCM.2023.231"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JHEP.2020.04.008"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.5505\/kjms.2014.21043"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.IJREGI.2024.02.003"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2015.06.028"},{"key":"e_1_2_9_20_1","volume-title":"StatPearls","author":"Tripathi N.","year":"2023"},{"key":"e_1_2_9_21_1","unstructured":"World Health Organization.Hepatitis D.https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/hepatitis\u2010d2025."},{"key":"e_1_2_9_22_1","unstructured":"World Health Organization.Hepatitis C.https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/hepatitis\u2010c2025."},{"key":"e_1_2_9_23_1","unstructured":"World Health Organization.Hepatitis B.https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/hepatitis\u2010b2025."},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.15656\/KJCG.2023.24.3.93"}],"container-title":["Public Health Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phn.70148","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/phn.70148","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phn.70148","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T08:53:51Z","timestamp":1788339231000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phn.70148"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,1]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/phn.70148"],"URL":"https:\/\/doi.org\/10.1111\/phn.70148","archive":["Portico"],"relation":{},"ISSN":["0737-1209","1525-1446"],"issn-type":[{"value":"0737-1209","type":"print"},{"value":"1525-1446","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,1]]},"assertion":[{"value":"2025-05-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}