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The protection by Thai plants extracts against <jats:styled-content style=\"fixed-case\">UVB DNA<\/jats:styled-content> damage and cytotoxicity was investigated in human keratinocytes. Petroleum ether, dichloromethane and ethanol extracts were prepared from 15 Thai herb species, and the total phenolic and flavonoid contents, the antioxidant and <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010absorbing properties were assessed by standard procedures. Cytoprotective effects were evaluated on the basis of cell survival, caspase\u20103 activity and pyrimidine dimers determination. High total phenolic and flavonoid contents were found in the ethanol and dichloromethane fractions. Dichloromethane extract of turmeric was shown to possess the highest antioxidant activity. The maximum <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content> absorptions were found in the ethanol extract of turmeric and in the dichloromethane extract of ginger. These extracts stimulated the synthesis of Thioredoxin 1, an antioxidant protein, and could protect human <jats:styled-content style=\"fixed-case\">HaCaT<\/jats:styled-content> keratinocytes from <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010induced <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> damage and cytotoxicity. The present data support the utilization of turmeric and ginger extracts in anti\u2010<jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content> cosmetic pharmaceuticals.<\/jats:p>","DOI":"10.1111\/php.12153","type":"journal-article","created":{"date-parts":[[2013,8,12]],"date-time":"2013-08-12T09:54:44Z","timestamp":1376301284000},"page":"214-224","source":"Crossref","is-referenced-by-count":14,"title":["Protection from <scp>UVB<\/scp> Toxicity in Human Keratinocytes by Thailand Native Herbs Extracts"],"prefix":"10.1111","volume":"90","author":[{"given":"Visa","family":"Thongrakard","sequence":"first","affiliation":[{"name":"Ph.D. Program in Clinical Biochemistry and Molecular Medicine Department of Clinical Chemistry Faculty of Allied Health Sciences, Chulalongkorn University Bangkok Thailand"},{"name":"Laboratorio di Patologia Molecolare Dipartimento di Scienze della Salute Universit\u00e0 del Piemonte Orientale Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nijsiri","family":"Ruangrungsi","sequence":"additional","affiliation":[{"name":"College of Public Health Sciences Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maneerat","family":"Ekkapongpisit","sequence":"additional","affiliation":[{"name":"Laboratorio di Patologia Molecolare Dipartimento di Scienze della Salute Universit\u00e0 del Piemonte Orientale Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciro","family":"Isidoro","sequence":"additional","affiliation":[{"name":"Laboratorio di Patologia Molecolare Dipartimento di Scienze della Salute Universit\u00e0 del Piemonte Orientale Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tewin","family":"Tencomnao","sequence":"additional","affiliation":[{"name":"Center for Excellence in Omics\u2010Nano Medical Technology Development Project Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,9,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2003.08.019"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553000902740150"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2007.00293.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2011.00601.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2012.03.007"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2011.01.027"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2009.12.019"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12137"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2009.1239"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(99)99017-1"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/00218839.1998.11100961"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0023-6438(95)80008-5"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0308-8146(00)00324-1"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5701001"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2012.06.025"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.2603"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf803537k"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfca.2011.01.008"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/09637486.2011.634788"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/09637486.2011.641942"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2010.12.042"},{"key":"e_1_2_6_23_1","first-page":"39","article-title":"Protective effect of inositol hexaphosphate against UVB damage in HaCaT cells and skin carcinogenesis in SKH1 hairless mice","volume":"61","author":"Williams K. 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