{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T05:08:12Z","timestamp":1759813692291},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,5]],"date-time":"2014-03-05T00:00:00Z","timestamp":1393977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photochem &amp; Photobiology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mycosis fungoides (<jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>) and parapsoriasis (<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>) are major dermatologic conditions for which phototherapy continues to be a successful and valuable treatment option. <jats:styled-content style=\"fixed-case\">UVA<\/jats:styled-content>\u20101 phototherapy is effective in the management of cutaneous <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\u2010cell mediated diseases. The aim of the study was to evaluate the efficacy and safety of low\u2010dose <jats:styled-content style=\"fixed-case\">UVA<\/jats:styled-content>\u20101 phototherapy for the management of <jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>\/early\u2010stage <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>. A total of 30 patients, diagnosed with <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> (<jats:italic>n<\/jats:italic>:19) or <jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content> (<jats:italic>n<\/jats:italic>:11) were enrolled to the study. All patients were managed with low\u2010dose <jats:styled-content style=\"fixed-case\">UVA<\/jats:styled-content>\u20101 (20 or 30\u00a0J\u00a0cm<jats:sup>\u22122<\/jats:sup>). Response was assessed clinically and immunohistochemically. <jats:styled-content style=\"fixed-case\">UVA<\/jats:styled-content>\u20101 treatment led to clinical and histological complete remission (<jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>) in 11 of 19 <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> patients (57.9%), partial remission (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>) in three of 19 (15.8%), after a mean cumulative dose of 1665 (range, 860\u20133120) J\u00a0cm<jats:sup>\u22122<\/jats:sup> and mean number of 73 exposure (range, 43\u2013107) sessions. Five patients with <jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content> (45.5%) showed <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> was observed in six patients with <jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content> (54.5%) after a mean cumulative dose of 1723 (range, 1060\u20133030) J\u00a0cm<jats:sup>\u22122<\/jats:sup> and mean number of 74 exposure (range, 53\u2013101) sessions. We conclude that low\u2010dose <jats:styled-content style=\"fixed-case\">UVA<\/jats:styled-content>\u20101 therapy seems to be an effective, safe, and well\u2010tolerated treatment option for patients with <jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>\/early\u2010stage <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/php.12253","type":"journal-article","created":{"date-parts":[[2014,2,6]],"date-time":"2014-02-06T22:46:37Z","timestamp":1391726797000},"page":"873-877","source":"Crossref","is-referenced-by-count":11,"title":["Efficacy of Low\u2010Dose Ultraviolet A\u20101 Phototherapy for Parapsoriasis\/Early\u2010Stage Mycosis Fungoides"],"prefix":"10.1111","volume":"90","author":[{"given":"Kenan","family":"Aydogan","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology Uludag University School of Medicine Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serkan","family":"Yazici","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Uludag University School of Medicine Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saduman","family":"Balaban Adim","sequence":"additional","affiliation":[{"name":"Department of Pathology Uludag University School of Medicine Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isil","family":"Tilki Gunay","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Uludag University School of Medicine Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferah","family":"Budak","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases Uludag University School of Medicine Immunology Unit Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayriye","family":"Saricaoglu","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Uludag University School of Medicine Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukran","family":"Tunali","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Uludag University School of Medicine Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emel","family":"Bulbul Baskan","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Uludag University School of Medicine Bursa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-03-055749"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2007.08.004"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.04427.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.32.0630"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/114.3.467"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197608)38:2<683::AID-CNCR2820380210>3.0.CO;2-V"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(82)70029-5"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.11.1377"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2005.00183.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000161114"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2006.01.025"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202X.2003.22106.x"},{"key":"e_1_2_6_14_1","first-page":"768","article-title":"Ultraviolet\u2010A1 phototherapy improves the status of the skin in cutaneous T\u2010cell lymphoma","volume":"140","author":"Kobyletzki G.","year":"1999","journal-title":"Br. 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