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James E. Cleaver's career (initiated in the early 1960s) has been devoted to the study of mammalian ultraviolet radiation (<jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>) photobiology, specifically the molecular genetics of xeroderma pigmentosum and other human diseases caused by defects in<jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>damage recognition and repair. This work by Jim and others has influenced the study of<jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>damage and repair in a variety of taxa. Today, the field of<jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>repair is enhancing our understanding of not only how to treat and prevent human disease, but is providing insights on the evolutionary history of life on Earth and how natural populations are coping with<jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>\u2010induced<jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>damage from anthropogenic changes in the environment such as ozone depletion.<\/jats:p>","DOI":"10.1111\/php.12388","type":"journal-article","created":{"date-parts":[[2014,11,14]],"date-time":"2014-11-14T06:39:48Z","timestamp":1415947188000},"page":"460-474","source":"Crossref","is-referenced-by-count":9,"title":["Beyond Xeroderma Pigmentosum:<scp>DNA<\/scp>Damage and Repair in an Ecological Context. A Tribute to James E. 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