{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:18:21Z","timestamp":1773015501037,"version":"3.50.1"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photochem &amp; Photobiology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study evaluated the influence of Doxycycline (DOX) and Low\u2010Intensity Laser (LIL) (InGaAlP diode laser) as scaling and root planing (SRP) adjuvants in the treatment of periodontitis induced in rats. The rats received periodontal disease induction, and after 7\u00a0days, the ligature was removed, and the animals were divided into groups\/treatments: NT\u2014receive no treatment; SRP\u2014submitted only to SRP; DOX\u2014submitted to SRP and DOX irrigation; LIL\u2014submitted to SRP and LIL irradiation; and DOX\u00a0+\u00a0LIL\u2014submitted to SRP treatments, DOX irrigation and LIL irradiation. The animals were sacrificed at 7, 15 and 30\u00a0days, and then, the analyses were performed. A lower concentration of Alpha\u2010glycoprotein acid and Complement 3 was observed in the DOX\u00a0+\u00a0LIL group compared to all the other groups in all the periods, and for Complement 4 at 15 and 30\u00a0days (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a00.01). A lower bone loss (BL) was observed in the DOX\u00a0+\u00a0LIL group compared to all the other groups in all the periods (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a00.01). It can be concluded that LIL was effective in the reduction of proteins, and its association with DOX was effective in the reduction of proteins and BL, in the treatment of periodontal induction in rats.\n                  <\/jats:p>","DOI":"10.1111\/php.13414","type":"journal-article","created":{"date-parts":[[2021,3,13]],"date-time":"2021-03-13T11:48:41Z","timestamp":1615636121000},"page":"1104-1115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Influence of Doxycycline and InGaAlP Diode Laser at 660 nm Wavelength in the Treatment of Periodontitis Induced in Rats:\n                    <i>In Vivo<\/i>\n                    Study"],"prefix":"10.1111","volume":"97","author":[{"given":"Glauco Rodrigues Carmo","family":"Silveira","sequence":"first","affiliation":[{"name":"Faculty of Dentistry Federal University of Alfenas (UNIFAL\u2010MG) Alfenas Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela Coelho","family":"de Lima","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Federal University of Alfenas (UNIFAL\u2010MG) Alfenas Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciano Tavares \u00c2ngelo","family":"Cintra","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Department of Restorative Dentistry S\u00e3o Paulo State University (UNESP) Ara\u00e7atuba, S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma\u00edsa Ribeiro Pereira Lima","family":"Brigag\u00e3o","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Department of Biochemistry Federal University of Alfenas (UNIFAL\u2010MG) Alfenas Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ed\u00edlson","family":"Ervolino","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Department of Basic Sciences S\u00e3o Paulo State University (UNESP) Ara\u00e7atuba, S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2227-5366","authenticated-orcid":false,"given":"Leandro Ara\u00fajo","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Federal University of Alfenas (UNIFAL\u2010MG) Alfenas Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,25]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1504","article-title":"Periodontal disease and its prevention, by traditional and new avenues","volume":"19","author":"Mann J.","year":"2020","journal-title":"Exper. 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