{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:54:22Z","timestamp":1747187662878,"version":"3.40.5"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T00:00:00Z","timestamp":1669161600000},"content-version":"am","delay-in-days":347,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T00:00:00Z","timestamp":1639180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000165","name":"Division of Chemistry","doi-asserted-by":"publisher","award":["CHE\u20100955361","CHE\u20102004088"],"award-info":[{"award-number":["CHE\u20100955361","CHE\u20102004088"]}],"id":[{"id":"10.13039\/100000165","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photochem &amp; Photobiology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>CTEA (<jats:italic>N,N<\/jats:italic>\u2010bis[2\u2010(carboxylmethyl)thioethyl]amine) is a mixed donor ligand that has been incorporated into multiple fluorescent sensors such as NiSensor\u20101 that was reported to be selective for Ni<jats:sup>2+<\/jats:sup>. Other metal ions such as Zn<jats:sup>2+<\/jats:sup> do not produce an emission response in aqueous solution. To investigate the coordination chemistry and selectivity of this receptor, we prepared NiCast, a photocage containing the CTEA receptor. Cast photocages undergo a photoreaction that decreases electron density on a metal\u2010bound aniline nitrogen atom, which shifts the binding equilibrium toward unbound metal ion. The unique selectivity of CTEA was examined by measuring the binding affinity of NiCast and the CTEA receptor for Ni<jats:sup>2+<\/jats:sup>, Zn<jats:sup>2+<\/jats:sup>, Cd<jats:sup>2+<\/jats:sup> and Cu<jats:sup>2+<\/jats:sup> under different conditions. In aqueous solution, Ni<jats:sup>2+<\/jats:sup> binds more strongly to the aniline nitrogen atom than Cd<jats:sup>2+<\/jats:sup>; however, in CH<jats:sub>3<\/jats:sub>CN, the change in affinity virtually disappears. The crystal structure of [Cu(CTEA)], which exhibits a Jahn\u2013Teller\u2013distorted square pyramidal structure, was also analyzed to gain more insight into the underlying coordination chemistry. These studies suggest that the fluorescence selectivity of NiSensor\u20101 in aqueous solution is due to a stronger interaction between the aniline nitrogen atom and Ni<jats:sup>2+<\/jats:sup> compared to other divalent metal ions except Cu<jats:sup>2+<\/jats:sup>.<\/jats:p>","DOI":"10.1111\/php.13567","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T01:43:55Z","timestamp":1637718235000},"page":"362-370","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Probing the Ni<sup>2+<\/sup>\u2010selective Response of Fluorescent Probe NiSensor\u20101 with the NiCast Photocaged Complex<sup>\u2020<\/sup><sup>\u2021<\/sup>"],"prefix":"10.1111","volume":"98","author":[{"given":"Erin E.","family":"Hickey","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry Worcester Polytechnic Institute Worcester MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel P.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Lonza Biologics Portsmouth NH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celina","family":"Gwizdala","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry Worcester Polytechnic Institute Worcester MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prem N.","family":"Basa","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry Worcester Polytechnic Institute Worcester MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Chemistry Massachusetts Institute of Technology Cambridge MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"MacDonald","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry Worcester Polytechnic Institute Worcester MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2176-0776","authenticated-orcid":false,"given":"Shawn C.","family":"Burdette","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry Worcester Polytechnic Institute Worcester MA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.01918.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1991.tb04320.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02244.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr900010n"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5CS00005J"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4CS00285G"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4CS00334A"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr960386p"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja906500m"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2020.213462"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2009.08.002"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201103191"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi3001769"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/b913605c"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/ic901182c"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejic.201000673"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2012.01136.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/ol101726a"},{"volume-title":"SAINT","year":"2011","author":"Bruker","key":"e_1_2_6_20_1"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1107\/S1600576714022985"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1107\/S2053273314026370"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1107\/S2053273314026370"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/08893110802547240"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1107\/S0108767304098800"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889807059870"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/ol900902z"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/jo061809i"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2dt30135k"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/ic400465g"}],"container-title":["Photochemistry 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