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We measured the total rate constants of singlet oxygen removal (\n                    <jats:italic>k<\/jats:italic>\n                    <jats:sub>T<\/jats:sub>\n                    ) by the methylated resveratrol derivative 1,3\u2010dimethoxy\u20105\u2010[(E)\u20102\u2010(4\u2010methoxyphenyl)ethenyl]benzene, and the partially methylated resveratrol derivatives 4\u2010((E)\u20102\u2010(3,5\u2010dimethoxyphenyl)ethenyl)phenol (pterostilbene), 5\u2010[(E)\u20102\u2010(4\u2010methoxyphenyl)ethenyl]benzene\u20101,3\u2010diol and (2\n                    <jats:italic>R<\/jats:italic>\n                    ,3\n                    <jats:italic>R<\/jats:italic>\n                    )\u20103,5,7\u2010trihydroxy\u20102\u2010(3,4,5\u2010trihydroxyphenyl)\u20102,3\u2010dihydrochromen\u20104\u2010one (dihydromyricetin). A protic solvent system results in higher\n                    <jats:italic>k<\/jats:italic>\n                    <jats:sub>T<\/jats:sub>\n                    values, except for the completely methylated derivative. We also investigated the ability of\n                    <jats:italic>trans<\/jats:italic>\n                    \u2010resveratrol to directly act as a photosensitizer (rather than\n                    <jats:italic>via<\/jats:italic>\n                    secondary photoproducts resulting from other primary photochemical reactions) for the production of singlet oxygen but found that neither resveratrol nor any of its derivatives are able to do so. We then studied the chemical reactions of the methylated derivative with singlet oxygen. The main pathway consists of a [4\u2009+\u20092] cycloaddition reaction involving the\n                    <jats:italic>trans<\/jats:italic>\n                    \u2010double bond and the\n                    <jats:italic>para<\/jats:italic>\n                    \u2010substituted benzene ring similar to what has been observed for\n                    <jats:italic>trans<\/jats:italic>\n                    \u2010resveratrol. Unlike\n                    <jats:italic>trans<\/jats:italic>\n                    \u2010resveratrol, the primary singlet oxygen product undergoes a second [4\u2009+\u20092] cycloaddition with singlet oxygen leading to the formation of diendoperoxides. A second reactivity pathway for both\n                    <jats:italic>trans<\/jats:italic>\n                    \u2010resveratrol and the methylated derivative leads to the formation of aldehydes\n                    <jats:italic>via<\/jats:italic>\n                    cleavage of a transient dioxetane.\n                  <\/jats:p>","DOI":"10.1111\/php.13704","type":"journal-article","created":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T21:04:13Z","timestamp":1661720653000},"page":"672-679","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Singlet Oxygen Quenching by Resveratrol Derivatives\n                    <sup>\u2020<\/sup>"],"prefix":"10.1111","volume":"99","author":[{"given":"Charlotte G.","family":"Monsour","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry California State University  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abegail C.","family":"Tadle","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry California State University  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bliss J.","family":"Tafolla\u2010Aguirre","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry California State University  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidhi","family":"Lakshmanan","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry California State University  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Hyeok","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry California State University  Los Angeles CA 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