{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:55:11Z","timestamp":1747187711250,"version":"3.40.5"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T00:00:00Z","timestamp":1705622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photochem &amp; Photobiology"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Laser photobiomodulation (<jats:styled-content style=\"fixed-case\">LPBM<\/jats:styled-content>) has been shown to be one of the possible modulating agents of inflammation. Similarly, medicinal plants, such as chamomile (<jats:italic>Matricaria recutita<\/jats:italic>) are also used with the same purpose. To evaluate tissue repair in the dorsum of the tongue of rats under topical use of chamomile alone and in association with LPBM. Seventy\u2010five male Wistar rats received a standardized wound on the dorsum of the tongue and were allocated into experimental groups: Control (G1), Chamomile Fluid extract (G2), Chamomile Infusion (G3), Laser (G4), Chamomile Infusion + Laser (G5). Euthanasia was done on days 3, 7, and 14 after surgery. Ulcers were evaluated and measured with a caliper. Sections stained with hematoxylin and eosin and Picrosirius Red allowed evaluation of edema, inflammatory infiltrate, cellularity, and re\u2010epithelialization and characterization of total collagen. Histomorphometric analysis of the percentage of total collagen, the distance from the basal layer to the epithelial surface, and the thickness of the stratum corneum were performed. The G2 and G4 groups modulated the exudative and proliferative phases of inflammation, both clinically and histologically. The G3 and G5 groups did not show significant differences in relation to the G1 group in most of the evaluated parameters. Chamomile fluid extract and LPBM alone showed better clinical and histological responses for tissue repair than the association between these therapeutic modalities. There were differences in the parameters of clinical, histological, and histomorphometric patterns between the experimental groups of the present investigation. The LPBM proved to be superior in the performed analysis.<\/jats:p>","DOI":"10.1111\/php.13901","type":"journal-article","created":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T12:04:56Z","timestamp":1705665896000},"page":"1431-1445","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the use of chamomile in isolation and in association with laser photobiomodulation in the healing of rats oral mucosa"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9676-9185","authenticated-orcid":false,"given":"Tila","family":"Fortuna","sequence":"first","affiliation":[{"name":"Interactive Processes of Organs and Systems, Institute of Health Sciences, Federal University of Bahia (ICS, UFBA)  Salvador Bahia Brasil"},{"name":"Bahiana School of Medicine and Public Health  Salvador Bahia Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana Borges","family":"Dantas","sequence":"additional","affiliation":[{"name":"Interactive Processes of Organs and Systems, Institute of Health Sciences, Federal University of Bahia (ICS, UFBA)  Salvador Bahia Brasil"},{"name":"Bahia Adventist College  Salvador Bahia Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rejane Concei\u00e7\u00e3o","family":"Santana","sequence":"additional","affiliation":[{"name":"Human Pathology from UFBA, Institute of Health Sciences at the Federal University of Bahia (ICS, UFBA)  Salvador Bahia Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hort\u00eancia Resende","family":"Della\u00a0Cella","sequence":"additional","affiliation":[{"name":"Interactive Processes of Organs and Systems. Institute of Health Sciences, Federal University of Bahia (ICS, UFBA)  Salvador Bahia Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elis\u00e2ngela","family":"de Jesus\u00a0Campos","sequence":"additional","affiliation":[{"name":"Medicine and Health from UFBA, Institute of Health Sciences at the Federal University of Bahia (ICS, UFBA)  Salvador Bahia Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela Botelho","family":"Martins","sequence":"additional","affiliation":[{"name":"Clinical Stomatology from PUCRS, Institute of Health Sciences at the Federal University of Bahia (ICS, UFBA)  Salvador Bahia Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034509359125"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20164741"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.18.12.128002"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2008.0"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/pho2007.2151"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2217\/rme.15.82"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.19082\/3024"},{"issue":"3","key":"e_1_2_7_9_1","first-page":"106","article-title":"Plant\u2010derived bioactives in oral mucosal lesions: a key emphasis to curcumin, lycopene, chamomile, aloe vera, green tea and coffee properties","volume":"9","author":"Salehi B","year":"2019","journal-title":"Biomol Ther"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.5001\/omj.2011.115"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfami.7.6.523"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.1900"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000357477"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/1981-863720180002000033328"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/4392184"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-018-0981-8"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.4317\/jced.51472"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-019-04890-2"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33100"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/dj8030087"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.27098"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-016-3279-y"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2016.08.001"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/ncc.000000000000019"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2014.3772"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-010-0875-0"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000411"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.2612"},{"key":"e_1_2_7_29_1","first-page":"800p","volume-title":"Statistical Methods for Rates and Proportions","author":"Fleiss JL","year":"2013"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-39842007000200009"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAI.0000000000000880"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12861"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-011-0971-5"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-014-1644-y"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-016-2071-z"}],"container-title":["Photochemistry and Photobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/php.13901","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T13:28:36Z","timestamp":1727184516000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/php.13901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,19]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/php.13901"],"URL":"https:\/\/doi.org\/10.1111\/php.13901","archive":["Portico"],"relation":{},"ISSN":["0031-8655","1751-1097"],"issn-type":[{"type":"print","value":"0031-8655"},{"type":"electronic","value":"1751-1097"}],"subject":[],"published":{"date-parts":[[2024,1,19]]},"assertion":[{"value":"2022-11-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}