{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:55:17Z","timestamp":1747187717742,"version":"3.40.5"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photochem &amp; Photobiology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Healthcare\u2010associated infections (HAI) are illnesses acquired during healthcare and are often the most important adverse event during healthcare. With the aim of increasing the effectiveness of disinfection\/decontamination processes in the health service with safe and not promote microbial resistance, we propose the development of portable equipment associated with type C ultraviolet light (UVC). The efficiency of the irradiance emitted by the equipment (at dosages 3.5, 5.0, and 60\u2009mJ\/cm<jats:sup>2<\/jats:sup>) was determined by the action exerted after exposure against four different bacterial (<jats:italic>Acinetobacter baumannii<\/jats:italic>, <jats:italic>Escherichia coli<\/jats:italic>, <jats:italic>Pseudomonas aeruginosa<\/jats:italic>, and <jats:italic>Staphylococcus aureus<\/jats:italic>) and three different fungi (<jats:italic>Candida albicans<\/jats:italic>, <jats:italic>C. parapsilosis<\/jats:italic>, and <jats:italic>Aspergillus<\/jats:italic> section <jats:italic>Fumigati<\/jats:italic>). It was possible to observe that all treatments were capable of inactivating the bacterial species evaluated (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), causing the irreversible death of these microorganisms. The most effective elimination of fungal agents was at a dose of 60\u2009mJ\/cm<jats:sup>2<\/jats:sup> of UVC radiation, with a decrease in the fungal inoculum varying between 94% and 100% in relation to the control without exposure. Thus, our study showed that the application of the portable prototype with UVC light (254\u2009nm) at a distance of 48\u2009mm, allowed an average irradiance of 3.5\u2009mW\/cm<jats:sup>2<\/jats:sup>, with doses of 3.5\u2009\u2248\u200960\u2009mJ\/cm<jats:sup>2<\/jats:sup> (from 1 to 60\u2009s of exposure), which can promote the total reduction of the bacteria evaluated and significantly reduce fungal growth. Therefore, this prototype could be used safely and effectively in the hospital environment, considerably reducing contamination and contributing to the reduction of healthcare\u2010associated infection risk.<\/jats:p>","DOI":"10.1111\/php.13945","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T09:45:49Z","timestamp":1712223949000},"page":"1827-1832","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Highly effective decontamination in a hospital environment: An easy\u2010to\u2010operate, low\u2010cost prototype"],"prefix":"10.1111","volume":"100","author":[{"given":"Clarice","family":"de la Rocha","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Desenvolvimento de Novos F\u00e1rmacos (LADEFA) Universidade Federal do Rio Grande\u2013FURG  Rio Grande Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina da Silva Canielles","family":"Caprara","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Desenvolvimento de Novos F\u00e1rmacos (LADEFA) Universidade Federal do Rio Grande\u2013FURG  Rio Grande Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanice Rodrigues","family":"Poester","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Micologia\u2013Faculdade de Medicina FURG  Rio Grande Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa Orzechowski","family":"Xavier","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Micologia\u2013Faculdade de Medicina FURG  Rio Grande Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anderson Favero","family":"Porte","sequence":"additional","affiliation":[{"name":"Instituto Federal de Educa\u00e7\u00e3o, Ci\u00eancia e Tecnologia do Rio Grande do Sul  Rio Grande Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo Moraes","family":"Galar\u00e7a","sequence":"additional","affiliation":[{"name":"Instituto Federal de Educa\u00e7\u00e3o, Ci\u00eancia e Tecnologia do Rio Grande do Sul  Rio Grande Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daza de Moraes Vaz Batista","family":"Filgueira","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Cultura Celular\u2010P\u00f3s\u2010gradua\u00e7\u00e3o em Ci\u00eancias Fisiol\u00f3gicas Instituto de Ci\u00eancias Biol\u00f3gicas\u2013FURG  Rio Grande Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paula de Souza","family":"Votto","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Cultura Celular\u2010P\u00f3s\u2010gradua\u00e7\u00e3o em Ci\u00eancias Fisiol\u00f3gicas Instituto de Ci\u00eancias Biol\u00f3gicas\u2013FURG  Rio Grande Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6888-9553","authenticated-orcid":false,"given":"Daniela Fernandes","family":"Ramos","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Desenvolvimento de Novos F\u00e1rmacos (LADEFA) Universidade Federal do Rio Grande\u2013FURG  Rio Grande Rio Grande do Sul Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,4]]},"reference":[{"volume-title":"Patient Safety. 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