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The electronic search was conducted through six databases in October 2023, seeking studies relying on any kind of adjunctive photochemical therapy in treating inflammatory peri\u2010implant diseases (PIDs). To showcase the effect size, mean differences along with 95% confidence intervals were utilized. Forty\u2010seven studies were deemed eligible for qualitative synthesis, 14 of which were included in the meta\u2010analysis. Low\u2010level light therapy and photodynamic therapy led to enhanced improvements in clinical and radiographic indices, such as bone level (BL), bleeding on probing (BoP), clinical attachment level (CAL), and probing depth (PD), during the 3\u2010month follow\u2010up. However, the differences in efficacy between treatments incorporating adjunctive photochemical therapy and those relying solely on mechanical debridement, considered the gold standard, lessened over extended follow\u2010up periods of 6, 9, and 12\u2009months. Significant differences were observed when comparing the treatment outcomes following adjunctive photochemical therapy between obese and smoker patients with healthy subjects. Incorporating adjunctive photochemical therapy for PID treatment might improve clinical and radiographic parameters in a short\u2010term follow\u2010up of 3\u2009months, but longer\u2010term benefits appear comparable to routine treatments.<\/jats:p>","DOI":"10.1111\/php.14098","type":"journal-article","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T09:06:26Z","timestamp":1744967186000},"page":"163-197","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Adjunctive photochemical therapy for management of inflammatory peri\u2010implant diseases: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1155-7459","authenticated-orcid":false,"given":"Soheil","family":"Shahbazi","sequence":"first","affiliation":[{"name":"Research Institute for Dental Sciences, Dentofacial Deformities Research Center Shahid Beheshti University of Medical 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