{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:06:55Z","timestamp":1784545615454,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100011855","name":"National Commission on Research, Science and Technology","doi-asserted-by":"publisher","award":["Fiscal year 2567\u20102568"],"award-info":[{"award-number":["Fiscal year 2567\u20102568"]}],"id":[{"id":"10.13039\/501100011855","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photochem &amp; Photobiology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We aimed to compare the anticandidal effect among different preirradiation times, measure singlet oxygen levels, and investigate the correlation between candidal reduction and singlet oxygen formation in erythrosine\u2009+\u2009KI photodynamic therapy.\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    (ATCC10231) biofilms were treated with 100\/200\u2009\u03bcM erythrosine\u2009+\u2009100\u2009mM KI for 1, 3, or 5\u2009min before light\u2010emitting diode (520\u2009\u00b1\u200910\u2009nm, 250\u2009mW\/cm\n                    <jats:sup>2<\/jats:sup>\n                    , 20\u2009J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    ) irradiation. Phosphate\u2010buffered saline, and nystatin were negative and positive controls, respectively. Candidal cells were quantified using a drop plate assay. Singlet oxygen was measured using a 9,10\u2010dimethylanthacene probe at 375\/436\u2009nm emission\/excitation wavelengths. Median candidal counts and singlet oxygen formation were compared using Kruskal\u2013Wallis with Dunn test. A\n                    <jats:italic>p<\/jats:italic>\n                    \u2010value &lt;0.05 was considered significant. Spearman's correlation was used to correlate candidal reduction and singlet oxygen formation. All preirradiation times for 200\u2009\u03bcM erythrosine\u2009+\u2009100\u2009mM KI decreased candidal cells by 7.59 (IQR\u2009=\u20090.33) log\n                    <jats:sub>10<\/jats:sub>\n                    CFU\/mL. At a 1\u2010min preirradiation, this group significantly generated higher singlet oxygen than the positive control (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Singlet oxygen levels correlated mildly with candidal reduction in the lower erythrosine group but not the higher group, likely due to singlet oxygen saturation. A 1\u2010min preirradiation with 200\u2009\u03bcM erythrosine\u2009+\u2009100\u2009mM KI generates singlet oxygen to inhibit\n                    <jats:italic>C. albicans<\/jats:italic>\n                    biofilms and shows potential for clinical oral candidiasis treatment.\n                  <\/jats:p>","DOI":"10.1111\/php.70053","type":"journal-article","created":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T06:59:27Z","timestamp":1761980367000},"page":"949-960","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of preirradiation time of erythrosine\u2009+\u2009potassium iodide\u2010mediated photodynamic therapy on candidal inhibition and singlet oxygen formation"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4795-6221","authenticated-orcid":false,"given":"Teerasak","family":"Damrongrungruang","sequence":"first","affiliation":[{"name":"Division Oral Diagnosis, Department of Oral Biomedical Sciences, Faculty of Dentistry Khon Kaen University  Khon Kaen Thailand"},{"name":"Melatonin Research Program Khon Kaen Unviersity  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natnicha","family":"Jariamphan","sequence":"additional","affiliation":[{"name":"Division Oral Diagnosis, Department of Oral Biomedical Sciences, Faculty of Dentistry Khon Kaen University  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitichaya","family":"Pratumtip","sequence":"additional","affiliation":[{"name":"Division Oral Diagnosis, Department of Oral Biomedical Sciences, Faculty of Dentistry Khon Kaen University  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarosha","family":"Boonsriram","sequence":"additional","affiliation":[{"name":"Division Oral Diagnosis, Department of Oral Biomedical Sciences, Faculty of Dentistry Khon Kaen University  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5887-6716","authenticated-orcid":false,"given":"Prapassara","family":"Sirikarn","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Faculty of Public Health Khon Kaen University  Khon Kaen Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2016.01.002"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034475"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-1768165"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl021"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/app11083626"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano11112883"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2011.02042.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19020337"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2023.103628"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2016.03.049"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/20002297.2024.2369357"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2011.05.013"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2012.02.002"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2015.08.029"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2018.07.003"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26092405"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23123190"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00467-17"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2019.111730"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.10.2887-2890.2000"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02665"},{"key":"e_1_2_9_23_1","unstructured":"PreissR NettoI.[Homepage on the internet]. Australia; [updated 2020 January 14; cited 2024 Sep 18]. Safer Yeast Cell Viability Assays: Erythrosin B; [about 5 pages]. 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