{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:54:53Z","timestamp":1772160893707,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,3,5]],"date-time":"2013-03-05T00:00:00Z","timestamp":1362441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2013,4]]},"abstract":"Summary<\/jats:title>\n \n Background<\/jats:title>\n \n Topical photodynamic therapy with methyl aminolevulinate (\n MAL\u2010PDT<\/jats:styled-content>\n ) is a non\u2010surgical treatment for actinic keratoses,\n B<\/jats:styled-content>\n owen's disease and basal cell carcinoma.\n MAL\u2010PDT<\/jats:styled-content>\n is particularly useful in elderly patients, who often present co\u2010morbidities and\/or in whom surgical excision could be contraindicated.\n MAL\u2010PDT<\/jats:styled-content>\n is generally well tolerated; the most frequent acute adverse events include pain and burning sensation localized to the treatment area. We describe our observation of the occurrence of acute postoperative hypertension (\n APH<\/jats:styled-content>\n ) and hypertensive crisis, after a\n MAL\u2010PDT<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n BP<\/jats:styled-content>\n measurement was taken twice at 2\u2010min intervals, both before and shortly after the\n MAL\u2010PDT<\/jats:styled-content>\n session. A\n PH<\/jats:styled-content>\n was defined as an increase in systolic\n BP<\/jats:styled-content>\n by more than 20% or an increase in diastolic\n BP<\/jats:styled-content>\n to above 110\u2009\n mmHg<\/jats:styled-content>\n . Hypertensive crisis was defined as a systolic\n BP<\/jats:styled-content>\n \u2265\u2009180\u2009\n mmHg<\/jats:styled-content>\n or a diastolic\n BP<\/jats:styled-content>\n \u2265\u2009110\u2009\n mmHg<\/jats:styled-content>\n , with or without acute target organ involvement.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Prevalence of post\u2010\n MAL\u2010PDT APH<\/jats:styled-content>\n was 22%; 11% of patients developed hypertensive crisis after\n MAL\u2010PDT<\/jats:styled-content>\n , requiring immediate treatment.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n We highlight the importance of blood pressure measurement both before and after\n MAL\u2010PDT<\/jats:styled-content>\n session to identify high\u2010risk patients and to prevent potentially severe organ involvement subsequent to hypertensive crisis.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/phpp.12019","type":"journal-article","created":{"date-parts":[[2013,3,5]],"date-time":"2013-03-05T06:33:22Z","timestamp":1362465202000},"page":"73-77","source":"Crossref","is-referenced-by-count":19,"title":["Risk of acute postoperative hypertension after topical photodynamic therapy for non\u2010melanoma skin cancer"],"prefix":"10.1111","volume":"29","author":[{"given":"Riccardo G.","family":"Borroni","sequence":"first","affiliation":[{"name":"Molecular Diagnostics Laboratory and Institute of Dermatology Fondazione IRCCS Policlinico San Matteo Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Carugno","sequence":"additional","affiliation":[{"name":"Department of Clinical\u2010Surgical, Diagnostic and Pediatric Science Institute of Dermatology University of Pavia Fondazione IRCCS Policlinico San Matteo Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicol\u00f2","family":"Rivetti","sequence":"additional","affiliation":[{"name":"Department of Clinical\u2010Surgical, Diagnostic and Pediatric Science Institute of Dermatology University of Pavia Fondazione IRCCS Policlinico San Matteo Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eloisa","family":"Arbustini","sequence":"additional","affiliation":[{"name":"Molecular Diagnostics Laboratory and Institute of Dermatology Fondazione IRCCS Policlinico San Matteo Pavia Italy"},{"name":"Centre for Inherited Cardiovascular Diseases Fondazione IRCCS Policlinico San Matteo Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Brazzelli","sequence":"additional","affiliation":[{"name":"Department of Clinical\u2010Surgical, Diagnostic and Pediatric Science Institute of Dermatology University of Pavia Fondazione IRCCS Policlinico San Matteo Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.06.006"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08882.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03430.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1996.d01-1076.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2010.00560.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.08.062"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1101"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AIA.0b013e31825430fd"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.19.2560"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.142.6.722"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1987.00370110101015"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2010.03670.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.18.2363"}],"container-title":["Photodermatology, 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Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fphpp.12019","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T10:38:46Z","timestamp":1700649526000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phpp.12019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,5]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/phpp.12019"],"URL":"https:\/\/doi.org\/10.1111\/phpp.12019","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718018084.793478065","asserted-by":"object"}]},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,5]]}}}