{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T23:54:37Z","timestamp":1785196477213,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,12,3]],"date-time":"2013-12-03T00:00:00Z","timestamp":1386028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Over 10 years have passed since the first approval of a biologic agent for the treatment of psoriasis. No one can argue that the arrival of this entirely new, highly effective class of medications has not forever changed the therapeutic landscape for psoriasis. Traditional treatments such as phototherapy, however, remain both viable and effective therapies, both as standalone treatments and in combination with biologics. In general, synergistic effects are noted for combinations utilizing phototherapy; however, the long\u2010term impact of these combinations on skin cancer development has yet to be fully determined. Increasing financial pressures for cost\u2010effective therapies augment the appeal of phototherapy and other traditional treatments as compared with the more costly biologics. Phototherapy also remains strong outside the realm of psoriasis, in the management of atopic dermatitis, vitiligo, and cutaneous <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\u2010cell lymphoma, among other conditions. Phototherapy will remain a cornerstone in the management of psoriasis as well as nonpsoriatic skin conditions, as its efficacy is well known, its financial cost is reasonable, it is readily compatible with other therapeutics, and its utility is historically proven.<\/jats:p>","DOI":"10.1111\/phpp.12088","type":"journal-article","created":{"date-parts":[[2013,11,8]],"date-time":"2013-11-08T12:23:20Z","timestamp":1383913400000},"page":"3-7","source":"Crossref","is-referenced-by-count":27,"title":["Phototherapy, psoriasis, and the age of biologics"],"prefix":"10.1111","volume":"30","author":[{"given":"Elisabeth G.","family":"Richard","sequence":"first","affiliation":[{"name":"Dermatology Department Johns Hopkins University  Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"H\u00f6nigsmann","sequence":"additional","affiliation":[{"name":"Dermatology Department Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197412052912301"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","DOI":"10.1201\/b14272","volume-title":"Phototherapy and photochemotherapy of skin disease","author":"Morison WL","year":"2005"},{"key":"e_1_2_8_4_1","volume-title":"Photochemotherapy in dermatology","author":"Abel EA","year":"1992"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-5945-4-11"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11008.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2012.11124"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.2011.590475"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.02.039"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60725-4"},{"key":"e_1_2_8_11_1","first-page":"1447","article-title":"Biologic therapies for psoriasis. 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