{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T19:11:42Z","timestamp":1789931502607,"version":"4.0.1"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,10,13]],"date-time":"2014-10-13T00:00:00Z","timestamp":1413158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Norwegian Cancer Society"},{"name":"The South-Eastern Norway Regional Health Authority"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2015,1]]},"abstract":"Summary<\/jats:title>\n \n Background<\/jats:title>\n \n The incidence rates of skin cancer increase with decreasing latitude in most western countries. Ultraviolet (\n UV<\/jats:styled-content>\n ) radiation is a main risk factor for skin cancer.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We have studied the relationship between\n UV<\/jats:styled-content>\n exposure and skin cancer incidence rates of squamous cell carcinoma (\n SCC<\/jats:styled-content>\n ), basal cell carcinoma (\n BCC<\/jats:styled-content>\n ), and cutaneous melanoma (\n CM<\/jats:styled-content>\n ), and tried to fit different mathematical models to the experimental data.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The incidence\u2013\n UV<\/jats:styled-content>\n exposure relationship for all three cancers is best described by the power law: ln(RTD)\u2009=\u2009A\n b<\/jats:sub>\n \u00b7ln(annual\n \n UV\n Ery<\/jats:sub>\n <\/jats:styled-content>\n dose), with relative tumor density (\n RTD<\/jats:styled-content>\n ) being age\u2010adjusted incidence rate per unit area of skin, and the power parameter\n \n A\n b<\/jats:sub>\n <\/jats:styled-content>\n being the biological amplification factor. For\n SCC<\/jats:styled-content>\n , the\n RTD<\/jats:styled-content>\n is a factor of 16\u201319 times larger on the head than on the trunk. For\n BCC<\/jats:styled-content>\n , this factor is 7 and for\n CM<\/jats:styled-content>\n it is 0.9\u20131.3.\n \n A\n b<\/jats:sub>\n <\/jats:styled-content>\n for\n CM<\/jats:styled-content>\n has remained almost unchanged from the 1960s until recently.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The incidence\u2013sun exposure relationship for all three cancers is well described by the power law.\n SCC<\/jats:styled-content>\n is dependent on total\n UV<\/jats:styled-content>\n exposures, while\n BCC<\/jats:styled-content>\n , and even more\n CM<\/jats:styled-content>\n , is dependent also on exposure patterns, with intermittent exposures being most carcinogenic.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/phpp.12139","type":"journal-article","created":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T22:05:41Z","timestamp":1410473141000},"page":"26-35","source":"Crossref","is-referenced-by-count":112,"title":["The relationship between\n UV<\/scp>\n exposure and incidence of skin cancer"],"prefix":"10.1111","volume":"31","author":[{"given":"Johan","family":"Moan","sequence":"first","affiliation":[{"name":"Department of Radiation Biology Institute for Cancer Research The Norwegian Radium Hospital Oslo University Hospital Oslo Norway"},{"name":"Department of Physics University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mantas","family":"Grigalavicius","sequence":"additional","affiliation":[{"name":"Department of Radiation Biology Institute for Cancer Research The Norwegian Radium Hospital Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zivile","family":"Baturaite","sequence":"additional","affiliation":[{"name":"Department of Radiation Biology Institute for Cancer Research The Norwegian Radium Hospital Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arne","family":"Dahlback","sequence":"additional","affiliation":[{"name":"Department of Physics University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asta","family":"Juzeniene","sequence":"additional","affiliation":[{"name":"Department of Radiation Biology Institute for Cancer Research The Norwegian Radium Hospital Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","unstructured":"MoanJ DahlbackA.Ultraviolet radiation and skin cancer: epidemiological data from Scandinavia. 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