{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T10:02:49Z","timestamp":1696154569900},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,11,11]],"date-time":"2014-11-11T00:00:00Z","timestamp":1415664000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>It is known that the levels of hormones secreted from the pituitary gland are increased by ultraviolet <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>) eye irradiation. The ovaries are affected by the hormones secreted from the pituitary gland. Therefore, we observed the influence of <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> eye irradiation on the ovaries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this study, a 2.5\u2009kJ\/m<jats:sup>2<\/jats:sup> dose of <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> irradiation was delivered by a sunlamp to the eye or the ear of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>57<jats:styled-content style=\"fixed-case\">BL<\/jats:styled-content>\/6j female mice. Five days after <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> irradiation, we removed the ovaries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The plasma levels of \u03b1\u2010melanocyte\u2010stimulating hormone (\u03b1\u2010<jats:styled-content style=\"fixed-case\">MSH<\/jats:styled-content>), adrenocorticotropic hormone (<jats:styled-content style=\"fixed-case\">ACTH<\/jats:styled-content>), and \u03b2\u2010endorphin were increased 24\u2009h after <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> irradiation of either the eye or the ear. The amounts of <jats:styled-content style=\"fixed-case\">ACTH<\/jats:styled-content> and \u03b1\u2010<jats:styled-content style=\"fixed-case\">MSH<\/jats:styled-content> were decreased 5 days after <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> irradiation. However, the \u03b2\u2010endorphin level 5 days after <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> eye irradiation did not decrease. In addition, <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> eye irradiation increased the expression of dopa\u2010positive cells, tyrosinase, and dopa decarboxylase, and also increased the immunoreactivity of melanocortin\u20101 receptor in the ovaries. The dopamine content in the plasma was also increased.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results suggest that the melanin and dopamine systems of the ovary are affected by <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> eye irradiation, and the synthesized dopamine is maintained at high levels as \u03b2\u2010endorphin.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12143","type":"journal-article","created":{"date-parts":[[2014,10,24]],"date-time":"2014-10-24T08:05:10Z","timestamp":1414137910000},"page":"124-128","source":"Crossref","is-referenced-by-count":2,"title":["Detection of dopa\u2010positive cells in mouse ovaries in response to ocular exposure to ultraviolet <scp>B<\/scp> rays"],"prefix":"10.1111","volume":"31","author":[{"given":"Keiichi","family":"Hiramoto","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Science Suzuka University of Medical Science  Suzuka Japan"},{"name":"Department of Dermatology Osaka City University Graduate School of Medicine  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yurika","family":"Yamate","sequence":"additional","affiliation":[{"name":"Department of Dermatology Osaka City University Graduate School of Medicine  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shosuke","family":"Kawanishi","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Science Suzuka University of Medical Science  Suzuka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,11]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"931","article-title":"The reconstructed epidermis with melanocytes: a new tool to study pigmentation and photoprotection","volume":"45","author":"Cario\u2010Andre M","year":"1999","journal-title":"Cell Mol Biol (Noisy\u2010Le\u2010Grand)"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12505758"},{"key":"e_1_2_5_4_1","first-page":"30","article-title":"Biochemical observations in UV\u2010induced pigmentation","volume":"5","author":"Rorsman H","year":"1988","journal-title":"Photodermatol"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12004.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2010.03777.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2010.00822.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.113.110619"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00005-013-0218-1"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2000.80.3.979"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0045183"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2010.08.003"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2008.07.002"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1002489"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.7243\/2053-3640-2-1"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2011.244"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2003-1287"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fphpp.12143","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12143","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:28:09Z","timestamp":1695515289000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phpp.12143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,11]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1111\/phpp.12143"],"URL":"https:\/\/doi.org\/10.1111\/phpp.12143","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,11]]}}}