{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T23:28:03Z","timestamp":1783207683855,"version":"3.54.6"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,6,26]],"date-time":"2015-06-26T00:00:00Z","timestamp":1435276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Solar urticarial (<jats:styled-content style=\"fixed-case\">SU<\/jats:styled-content>) is characterized by erythema, whealing, and\/or pruritus occurring minutes after sun exposure. Treatment is difficult and often unsatisfactory.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the action spectra and minimal urticaria dose (<jats:styled-content style=\"fixed-case\">MUD<\/jats:styled-content>) and to tailor a treatment regimen graded according to disease severity in a series of patients with <jats:styled-content style=\"fixed-case\">SU<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Eleven patients (seven females, four males, age range: 5\u201360\u00a0years) with a clinical history suggestive of <jats:styled-content style=\"fixed-case\">SU<\/jats:styled-content>, verified by photo\u2010provocation tests to ultraviolet A (<jats:styled-content style=\"fixed-case\">UVA<\/jats:styled-content>), visible light, and\/or <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>, were treated with various combinations of antihistamines and leukotriene receptor antagonist.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All patients were sensitive to visible light (median <jats:styled-content style=\"fixed-case\">MUD<\/jats:styled-content> 50\u00a0J\/cm<jats:sup>2<\/jats:sup>). Three patients were sensitive to <jats:styled-content style=\"fixed-case\">UVA<\/jats:styled-content> (median <jats:styled-content style=\"fixed-case\">MUD<\/jats:styled-content> 3.75\u00a0J\/cm<jats:sup>2<\/jats:sup>), and one patient was sensitive to <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">MUD<\/jats:styled-content> of 0.03\u00a0J\/cm<jats:sup>2<\/jats:sup>). Two patients experienced a spontaneous remission without treatment. One patient declined treatment. The remaining eight patients were managed by a combination of antihistamines (desloratidine, fexofenadine, cetirizine <jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content>l) and a leukotriene receptor antagonist (montelukast). Seven of the 8 patients experienced a sustained remission of symptoms and signs following treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Photoprovocation for <jats:styled-content style=\"fixed-case\">SU<\/jats:styled-content> with determination of action spectra and <jats:styled-content style=\"fixed-case\">MUD<\/jats:styled-content> enables specifically tailored treatment regimens consisting of combinations of antihistamines and leukotriene receptor antagonist.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12186","type":"journal-article","created":{"date-parts":[[2015,6,6]],"date-time":"2015-06-06T15:41:44Z","timestamp":1433605304000},"page":"302-306","source":"Crossref","is-referenced-by-count":14,"title":["Treatment of solar urticaria using antihistamine and leukotriene receptor antagonist combinations tailored to disease severity"],"prefix":"10.1111","volume":"31","author":[{"given":"Assi","family":"Levi","sequence":"first","affiliation":[{"name":"Photodermatosis clinic and Laser unit, Department of Dermatology Rabin Medical Center Petah\u2010Tikva Israel"},{"name":"Department of Dermatology Hadassah\u2010Hebrew University Medical Center Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claes D.","family":"Enk","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hadassah\u2010Hebrew University Medical Center Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2004.01.005"},{"key":"e_1_2_6_3_1","first-page":"1149","article-title":"Characteristics and prognosis of idiopathic solar urticaria: a cohort of 87 cases","volume":"39","author":"Beattie PE","year":"2003","journal-title":"Arch Dermatol"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.08.020"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000246570"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0781.2002.00750.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.144.6.765"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/JAA.S3236"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.1997.tb00109.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(81)70065-3"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000320233"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2008.00386.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10944.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08581.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1684\/ejd.2013.1933","article-title":"Solar urticaria: a time\u2010extended retrospective series of 61 patients and review of the literature","volume":"23","author":"Du\u2010Thanh A","year":"2013","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08543.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12313"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fphpp.12186","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12186","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T16:09:23Z","timestamp":1695485363000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phpp.12186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,26]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1111\/phpp.12186"],"URL":"https:\/\/doi.org\/10.1111\/phpp.12186","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,26]]}}}