{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:52:51Z","timestamp":1791564771881,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T00:00:00Z","timestamp":1449619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009754","name":"Galderma","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009754","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Although conventional photodynamic therapy (c\u2010<jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>) using methyl aminolevulinate cream (<jats:styled-content style=\"fixed-case\">MAL<\/jats:styled-content>) is effective for the treatment of grade I\u2010<jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> facial and scalp actinic keratosis (<jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>), it is associated with treatment\u2010related pain for some patients. Daylight\u2010mediated PDT (<jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>) has shown similar efficacy to c\u2010<jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>, was nearly painless, and was well tolerated. Overall, <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content> effectively treats <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> and offers a simpler and better tolerated treatment option than c\u2010<jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>. This consensus panel provided recommendations on the use of <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content> in Latin America (<jats:styled-content style=\"fixed-case\">LATAM<\/jats:styled-content>) for the treatment of actinic damage associated with few or multiple <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>s. The panel was comprised of eight dermatologists from different <jats:styled-content style=\"fixed-case\">LATAM<\/jats:styled-content> countries who have experience using <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content> for the treatment of actinic damage. The panel reviewed the relevant literature and provided personal expertise with regard to using <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content> for the treatment of photodamage with or without <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>. The recommendations formulated by the expert panel provide evidence\u2010based guidelines on all aspects of <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content> for the treatment of actinic damage associated with <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content> in different regions of <jats:styled-content style=\"fixed-case\">LATAM<\/jats:styled-content>. These recommendations provide guidance for dermatologists to ensure maintenance of efficacy and safety of <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content> when treating actinic damage, associated with few or multiple <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>s in sun\u2010exposed skin.<\/jats:p>","DOI":"10.1111\/phpp.12221","type":"journal-article","created":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T09:16:42Z","timestamp":1446801402000},"page":"81-87","source":"Crossref","is-referenced-by-count":19,"title":["Daylight\u2010mediated photodynamic therapy for actinic damage in Latin America: consensus recommendations"],"prefix":"10.1111","volume":"32","author":[{"given":"Beni","family":"Grinblat","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital das Clinicas University of Sao Paulo Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaston","family":"Galimberti","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Hospital Italiano Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgardo","family":"Chouela","sequence":"additional","affiliation":[{"name":"Centro de Investigaciones Dermatol\u00f3gicas Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Sanclemente","sequence":"additional","affiliation":[{"name":"Group of Investigative Dermatology (GRID) School of Medicine University of Antioquia Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Lopez","sequence":"additional","affiliation":[{"name":"Cirug\u00eda Dermatol\u00f3gica y Oncolog\u00eda Cut\u00e1nea Department Hospital Militar \u201cDr. Carlos Arvelo\u201d Caracas Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Alcala","sequence":"additional","affiliation":[{"name":"Centro Dermatol\u00f3gico Dr. Ladislao de la Pascua Ciudad de M\u00e9xico Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu\u00eds","family":"Torezan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital das Clinicas University of Sao Paulo Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Pantoja","sequence":"additional","affiliation":[{"name":"Santiago Medical Institute Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10830.x"},{"key":"e_1_2_6_3_1","first-page":"529","article-title":"Data analysis of the Brazilian Society of Dermatology skin cancer prevention campaign, 1999 to 2005","volume":"81","author":"Socieda de Brasileira de Dermatologia","year":"2006","journal-title":"An Bras Dermatol"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03541.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb08544.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.09.052"},{"key":"e_1_2_6_7_1","first-page":"240","article-title":"Enfermedades de la piel mas frecuentes en la consultadermatol\u00f3gica del hospital universitario San Vicente de Pa\u00fal y del hospital infantil, Medell\u00edn, Colombia 1999","volume":"26","author":"Sanclemente G","year":"2001","journal-title":"Acta Med Col"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.103342"},{"key":"e_1_2_6_9_1","first-page":"201","article-title":"Progression of actinic keratosis to squamous cell carcinoma revisited: clinical and treatment implications","volume":"87","author":"Feldman SR","year":"2011","journal-title":"Cutis"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12530"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(91)70113-G"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07470.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08450.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09119.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10209.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10833.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13138"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13228"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12127"},{"key":"e_1_2_6_20_1","article-title":"Feasibility of daylight\u2010mediated photodynamic therapy for actinic keratosis throughout the year in Central and South America: A meteorological study","author":"Grinblat BM","year":"2015","journal-title":"Int J Dermatol"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550510042868"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12538"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04386.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12119_suppl"},{"key":"e_1_2_6_25_1","unstructured":"GholamP.Influence of pre\u2010treatment with urea cream 40% on face and scalp AK on efficacy and tolerability. Presented at the Euro\u2010PDT 14th Annual Congress; 4\u20105 April 2014; Nice France."},{"key":"e_1_2_6_26_1","unstructured":"Osman\u2010PonchetH.Effect of sunscreen on Metvix\u00aeabsorption in ex\u2010vivo human skin. Presented at the Euro\u2010PDT 14th Annual Congress; 4\u20105 April 2014; Nice France."},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1425"},{"key":"e_1_2_6_28_1","unstructured":"WulfH.Optimizing the amount of Metvix\u00aein daylight PDT. Presented at the Euro\u2010PDT 13th Annual Congress; 31 May 31 \u2013 1 June 2013; Madrid Spain."},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12882"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fphpp.12221","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12221","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/phpp.12221","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12221","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T09:55:49Z","timestamp":1695549349000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phpp.12221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,9]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1111\/phpp.12221"],"URL":"https:\/\/doi.org\/10.1111\/phpp.12221","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,9]]}}}