{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:23:00Z","timestamp":1790270580515,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,1,4]],"date-time":"2018-01-04T00:00:00Z","timestamp":1515024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2018,5]]},"abstract":"Summary<\/jats:title>\n \n Background<\/jats:title>\n \n Solar urticaria (\n SU<\/jats:styled-content>\n ) is a rare photodermatosis. Treatment is challenging, and outcomes are often disappointing. Omalizumab is an anti\u2010IgE, currently approved for treatment of chronic spontaneous urticaria. We sought to evaluate therapy with omalizumab in refractory\n SU<\/jats:styled-content>\n and describe predictive factors for response.\n <\/jats:p>\n <\/jats:sec>\n \n Materials\/methods<\/jats:title>\n \n Patients with refractory\n SU<\/jats:styled-content>\n under treatment with omalizumab were included in this study. Clinical outcome was evaluated using the Urticaria Activity Score 7 (\n UAS<\/jats:styled-content>\n 7), Dermatology Life Quality Index (\n DLQI<\/jats:styled-content>\n ) and Pruritus Visual Analogue Scale (\n VAS<\/jats:styled-content>\n ). Complete clinical response (\n CCR<\/jats:styled-content>\n ) was defined as having an\n UAS<\/jats:styled-content>\n 7\u00a0=\u00a00,\n DLQI<\/jats:styled-content>\n <6 and\n VAS<\/jats:styled-content>\n \u00a0=\u00a00. Phototesting was performed and compared to baseline. We performed a PubMed search to identify reported cases of\n SU<\/jats:styled-content>\n in adults treated with omalizumab, analysing their characteristics in order to predict response to omalizumab.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Eight patients were included. Median age was 45.5\u00a0years (range, 23\u201064). Light spectrum most commonly implicated was\n UV<\/jats:styled-content>\n \u2010A. Clinical outcomes: 89% (7\/8) achieved\n CCR<\/jats:styled-content>\n with omalizumab. Phototesting was normal in 42.8% (3\/7) of them. In our review, we identified 38 patients (including the current case series), and 68.4% showed favourable outcomes with omalizumab. Median time since onset of\n SU<\/jats:styled-content>\n was lower in responders.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Omalizumab can be an effective treatment in refractory\n SU<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/phpp.12370","type":"journal-article","created":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T11:22:40Z","timestamp":1511522560000},"page":"194-199","source":"Crossref","is-referenced-by-count":21,"title":["Clinical and photobiological response in eight patients with solar urticaria under treatment with omalizumab, and review of the literature"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4704-6132","authenticated-orcid":false,"given":"Daniel","family":"Morgado\u2010Carrasco","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Fust\u00e0\u2010Novell","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Podlipnik","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Combalia","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Aguilera","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Cl\u00ednic de Barcelona Universitat de Barcelona Barcelona 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