{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T01:31:44Z","timestamp":1768267904074,"version":"3.49.0"},"reference-count":6,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T00:00:00Z","timestamp":1544572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background\/Purpose<\/jats:title><jats:p>Screening antinuclear antibody (ANA) is not recommended prior to initiating narrowband ultraviolet B (NBUVB) phototherapy in vitiligo patients, unless concern for photosensitivity exists. Guidelines on prescribing NBUVB phototherapy in vitiligo patients with positive ANA are unavailable, prompting this study to uncover trends.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective chart review investigated patients 12\u00a0years of age or older with a diagnosis of vitiligo between January 2015 and September 2017, positive serum ANA, and NBUVB phototherapy. Demographic information, vitiligo type, ANA titer\/pattern, starting dose, peak dose without phototoxicity, phototherapy frequency, total number of phototoxic events and treatments, coexisting photosensitizing disorders, and concomitant photosensitizing medications were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven (two males, five females) of 1485 charts met inclusion criteria. One Caucasian, two African\u2010Americans, one Asian, and three Hispanic\/Latinos patients were represented. Six of seven patients had generalized vitiligo and one had focal vitiligo. ANA titer\/patterns and phototherapy frequencies were evaluated. Peak doses of NBUVB without phototoxic event were available in six of seven patients: 274, 290, 532, 618, 700, and 734\u00a0mJ\/cm<jats:sup>2<\/jats:sup>. Total number of phototoxic events varied: 1 (n\u00a0=\u00a01), 2 (n\u00a0=\u00a01), 4 (n\u00a0=\u00a01), 6 (n\u00a0=\u00a02), or 8 (n\u00a0=\u00a01). Total NBUVB treatments ranged between 6 and 132. Coexisting photosensitizing disorders were not identified. One patient had phototoxic events in association with photosensitizing medications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>With regard to phototoxicity, meaningful trends were not identified that may guide prescription of phototherapy in vitiligo patients with positive ANA, suggesting ANA may not be exclusionary criteria when prescribing NBUVB.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12430","type":"journal-article","created":{"date-parts":[[2018,9,29]],"date-time":"2018-09-29T15:44:22Z","timestamp":1538235862000},"page":"106-109","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The impact of positive antinuclear antibody on narrowband ultraviolet B phototherapy in patients with vitiligo: A retrospective chart review"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9766-0149","authenticated-orcid":false,"given":"Amanda F.","family":"Nahhas","sequence":"first","affiliation":[{"name":"Department of Dermatology Beaumont\u2010Farmington Hills  Farmington Hills Michigan"},{"name":"Department of Dermatology Henry Ford Hospital  Detroit Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan T.","family":"Nartker","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Wayne State University  Dearborn Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylor L.","family":"Braunberger","sequence":"additional","affiliation":[{"name":"Department of Dermatology Henry Ford Hospital  Detroit Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Henry Ford Hospital  Detroit Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iltefat H.","family":"Hamzavi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Henry Ford Hospital  Detroit Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.12.041"},{"key":"e_1_2_8_3_1","first-page":"607","volume-title":"Dermatology","author":"Jacobe H","year":"2012"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13544"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kel063"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000070942"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2012.01519.x"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fphpp.12430","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12430","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/phpp.12430","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12430","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T15:56:47Z","timestamp":1694707007000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phpp.12430"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,12]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1111\/phpp.12430"],"URL":"https:\/\/doi.org\/10.1111\/phpp.12430","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,12]]},"assertion":[{"value":"2018-03-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}