{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:22:03Z","timestamp":1793110923671,"version":"4.5.0"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,8]],"date-time":"2019-01-08T00:00:00Z","timestamp":1546905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007225","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["104\u20102314\u2010B\u2010010\u2010051 MY3"],"award-info":[{"award-number":["104\u20102314\u2010B\u2010010\u2010051 MY3"]}],"id":[{"id":"10.13039\/100007225","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010101","name":"Taichung Veterans General Hospital","doi-asserted-by":"publisher","award":["1066802C"],"award-info":[{"award-number":["1066802C"]}],"id":[{"id":"10.13039\/501100010101","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Narrowband ultraviolet B (<jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>) phototherapy is a widely used treatment for various dermatoses. The risk of skin cancer following long\u2010term <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> phototherapy has rarely been explored in skin phototypes <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\u2010V.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a nationwide\u2010matched cohort study and identified a total of 22\u00a0891 psoriasis patients starting <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> phototherapy from the Taiwan National Health Insurance Database during the period 2000\u20102013. Cumulative incidences of skin cancers were compared between subjects receiving less than 90 <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> treatments (S\u2010cohort, N\u00a0=\u00a013\u00a0260) and age\u2010 as well as propensity score\u2010matched subjects receiving more than or equal to 90 <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> treatments (L\u2010cohort, N\u00a0=\u00a03315).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no significant differences in the overall cumulative incidences of skin cancers between the two cohorts (log\u2010rank <jats:italic>t<\/jats:italic> test, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.691) during the follow\u2010up periods. The S\u2010cohort had a significantly lower prevalence of actinic keratosis when compared with the L\u2010cohort (0.54% vs 1.00%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.005).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Long\u2010term <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> phototherapy does not increase skin cancer risk compared with short\u2010term <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> phototherapy in psoriasis patients with skin phototypes <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\u2010V.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12443","type":"journal-article","created":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T14:38:25Z","timestamp":1544452705000},"page":"164-171","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Risk of skin cancer in psoriasis patients receiving long\u2010term narrowband ultraviolet phototherapy: Results from a Taiwanese population\u2010based cohort study"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0639-3533","authenticated-orcid":false,"given":"Teng\u2010Li","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Dermatology Taichung Veterans General Hospital  Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Ying","family":"Wu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Graduate 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