{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T04:23:57Z","timestamp":1783571037062,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,6,27]],"date-time":"2019-06-27T00:00:00Z","timestamp":1561593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100011002","name":"National Natural Science Foundation of China-Yunnan Joint Fund","doi-asserted-by":"publisher","award":["81773310"],"award-info":[{"award-number":["81773310"]}],"id":[{"id":"10.13039\/501100011002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the efficacy and safety of narrowband ultraviolet B (NB\u2010UVB) phototherapy in home vs in hospital for the management of limited new\u2010onset vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with new\u2010onset vitiligo (&lt;3\u00a0months) with &lt;5% body surface area involvement were recruited and randomly assigned to either a home\u2010based or a hospital\u2010based treatment group. Both groups were administered NB\u2010UVB phototherapy thrice a week. The body surface area (BSA) involved with vitiligo, Vitiligo Area Scoring Index (VASI), the effectiveness of repigmentation, Vitiligo Quality of Life index (VitiQoL), and the cost of treatment were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 100 patients completed the study. Patients in both groups exhibited improvements demonstrated by BSA and VSAI decrease. No significant differences were found between the two groups in terms of skin repigmentation (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). Improvements in the VitiQoL scores were reduced to the greatest degree at week 8 for all patients in both groups. Adverse events, such as painful erythema, burning, blistering, and excessive hyperpigmentation, were more frequently observed in the home\u2010based treatment group than in the hospital\u2010based treatment group. The cost of phototherapy in hospital exceeded the cost of home phototherapy after 7\u00a0weeks of treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Home NB\u2010UVB phototherapy treatment was as effective as treatment in hospital, but exhibited cost\u2010effective and a better compliance. However, the education of the patients should be strengthened to avoid excessive UVB exposure and related adverse events.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12495","type":"journal-article","created":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T18:53:47Z","timestamp":1560797627000},"page":"14-20","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Home vs hospital narrowband UVB treatment by a hand\u2010held unit for new\u2010onset vitiligo: A pilot randomized controlled study"],"prefix":"10.1111","volume":"36","author":[{"given":"Baoyi","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Dermatology Shanghai General Hospital, Shanghai Jiaotong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Dermatology Shanghai General Hospital, Shanghai Jiaotong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Dermatology Shanghai General Hospital, Shanghai Jiaotong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0760-6203","authenticated-orcid":false,"given":"Zhouwei","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Shanghai General Hospital, Shanghai Jiaotong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.10.048"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-018649"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02278.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2012.00648.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.114752"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.11.010"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.12.009"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.12.040"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08881.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.12.041"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/750342"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2017.1303570"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.01.038"},{"key":"e_1_2_6_15_1","first-page":"292","article-title":"Immunohistochemical study before and after narrow band (311 nm) UVB treatment in vitiligo","volume":"18","author":"Francesco V","year":"2008","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2006.00052"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c1490"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"18563","DOI":"10.5070\/D3196018563","article-title":"Explicit and implicit copayments for phototherapy: examining the cost of commuting","volume":"19","author":"Yentzer BA","year":"2013","journal-title":"Dermatol Online J"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.136907"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09678.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.12.026"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14993"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07136.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2014.01.011"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12326"}],"container-title":["Photodermatology, Photoimmunology &amp; 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