{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T04:22:24Z","timestamp":1783570944004,"version":"3.55.0"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,10,10]],"date-time":"2019-10-10T00:00:00Z","timestamp":1570665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003052","name":"Ministry of Trade, Industry and Energy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003052","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/purpose<\/jats:title><jats:p>Ultraviolet B (UVB) laser irradiation in a targeted manner is a reasonable treatment option for localized vitiligo. Recently, narrow\u2010band UVB gain\u2010switched 311\u2010nm titanium:sapphire lasers (TSL) were developed for the treatment of localized vitiligo. We aimed to compare efficacy, patient satisfaction, and safety between the conventional 308\u2010nm excimer laser (EL) and gain\u2010switched 311\u2010nm TSL in patients with vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The 13\u2010paired lesions from 10 patients who had small vitiligo patches were included in this prospective intra\u2010patient comparison trial. Each pair was randomly assigned to each laser treatment group and treated twice weekly for 12\u00a0weeks. The global photographic assessments by dermatologists, objective numerical assessments by imaging analyzer, and patient's satisfaction were used to evaluate the effectiveness. Adverse effects were also investigated at every visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All treated lesions showed improvement of about 50% after 12\u00a0weeks. There was no significant difference between EL\u2010 and TSL\u2010treated groups. Patient satisfaction and preference among the groups were also similar. Regarding safety, there were no serious adverse effects requiring cessation of the treatments; however, the severity score for persistent erythema (lasting &gt;24\u00a0hours) was significantly lower in the TSL group than in the EL group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The gain\u2010switched 311\u2010nm TSL exhibited similar efficacy to the 308\u2010nm EL in treating vitiligo as well as improved safety. Therefore, the 311\u2010nm TSL is considered as a candidate device to replace the EL as a new and promising treatment option for localized vitiligo.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12512","type":"journal-article","created":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T02:43:01Z","timestamp":1568428981000},"page":"97-104","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A comparative clinical trial to evaluate efficacy and safety of the 308\u2010nm excimer laser and the gain\u2010switched 311\u2010nm titanium:sapphire laser in the treatment of vitiligo"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5160-7932","authenticated-orcid":false,"given":"Myeong Jin","family":"Park","sequence":"first","affiliation":[{"name":"Department of Dermatology College of Medicine Dankook University Cheonan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3471-1428","authenticated-orcid":false,"given":"Uri","family":"Shon","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicine Dankook University Cheonan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8425-837X","authenticated-orcid":false,"given":"Gi Hyun","family":"Seong","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicine Dankook University Cheonan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9072-201X","authenticated-orcid":false,"given":"Myung Hwa","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicine Dankook University Cheonan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5449-8313","authenticated-orcid":false,"given":"Byung Cheol","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicine Dankook University Cheonan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0684-498X","authenticated-orcid":false,"given":"Seung Phil","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Dermatology Yonsei Wonju College of Medicine Yonsei University Wonju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.114752"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.121357"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2011.00606.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000335272"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11008.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.2175"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.12.040"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12015"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12199"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2007.00238.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12480997"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12326989"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12479366"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02151.x"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12512","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/phpp.12512","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12512","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T05:30:50Z","timestamp":1694064650000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phpp.12512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,10]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1111\/phpp.12512"],"URL":"https:\/\/doi.org\/10.1111\/phpp.12512","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,10]]},"assertion":[{"value":"2019-03-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}