{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T06:16:10Z","timestamp":1780467370026,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T00:00:00Z","timestamp":1586131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008055","name":"Fundaci\u00f3n Eugenio Rodr\u00edguez Pascual","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although systemic therapies are recommended for severe or recalcitrant cases of pityriasis versicolor (PV), they are not free of important side effects and drug interactions. Photodynamic therapy (PDT) utilizes the action of singlet oxygen and free radicals produced by a light\u2010activated photosensitizer to kill viruses, bacteria, or fungi. In this study, the effect of a PDT mediated by methylene blue (MB) in PV was evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Five women with PV disseminated on the back and diagnosed by fresh microscopic analysis were treated with a solution of MB (2%) applied to the PV lesions for 3\u00a0minutes. Next, a red LED lamp (\u03bb\u00a0=\u00a0630\u00b15\u00a0nm, 37\u00a0J\/cm<jats:sup>2<\/jats:sup>), placed 100\u00a0mm from the skin for 10\u00a0minutes, was applied on the dyed PV lesions. Six sessions of MB\/PDT were implemented with a 2\u2010week interval in between. Wood's lamp examination was used to monitor fungal infection at each time point.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complete cure was observed in the five women at the 4\u00a0weeks post\u2010treatment follow\u2010up. Fluoresce images from PV lesions by Wood's lamp allowed to evaluate whether the lesions were healed or not at each time point. No patient showed relapse at the 6\u2010month follow\u2010up. The patients did not have any adverse effect, and good cosmetic outcome was observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Six sessions of MB\/PDT spaced at 14\u2010day intervals are sufficient for the treatment for PV in healthy patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12555","type":"journal-article","created":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T16:29:50Z","timestamp":1584635390000},"page":"308-312","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Successful treatment of <i>Pityriasis Versicolor<\/i> by photodynamic therapy mediated by methylene blue"],"prefix":"10.1111","volume":"36","author":[{"given":"Enrique","family":"Alberdi","sequence":"first","affiliation":[{"name":"Private Clinic of Dr. Alberdi Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5265-2233","authenticated-orcid":false,"given":"Clara","family":"G\u00f3mez","sequence":"additional","affiliation":[{"name":"Institute of Physical Chemistry Rocasolano CSIC Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16521"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.12.022"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2004.01085.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1825"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S195166"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2002.00378.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.Supplement_2.S128"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.259"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2013.13062"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13116"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S124918"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04719.x"},{"key":"e_1_2_7_14_1","first-page":"145","article-title":"Current evidence and applications of photodynamic therapy in dermatology","volume":"7","author":"Wan MT","year":"2014","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.00202"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micres.2007.08.001"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.9.1218"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12042"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12420"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2017.10.013"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/php.12264"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2004.06.006"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1572-1000(05)00097-9"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2014.04.007"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874285801610010012"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/3759704"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.3889\/oamjms.2019.092"}],"container-title":["Photodermatology, Photoimmunology &amp; 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